LEADER 02067nam  2200469z- 450 
001 9910345962003321
005 20210211
035   $a(CKB)4920000000094094
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/42011
035   $a(oapen)doab42011
035   $a(EXLCZ)994920000000094094
100   $a20202102d2019      |y         0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 00$aBeyond Borders: Myotonic Dystrophies - A European Perception
210   $cFrontiers Media SA$d2019
215   $a1 online resource (148 p.)
225 1 $aFrontiers Research Topics
311 08$a2-88945-709-5 
330   $aMyotonic dystrophies (DMs) are pleotropic multisystemic diseases. These dominantly transmitted repeat disorders affect multiple organs of the human body at all ages - from the newborns to the elderly. The present Research Topic represents a timely addition to the expanding body of evidence which aims to provide novel perspectives in our understanding of myotonic dystrophies. This collection of original contributions and standpoint reviews from multiple leading DM centres in Europe describes the state of the art for the characterization of the DMs diseases, the development of molecular strategies to target its multisystemic nature, and provides evidence of screening and testing novel therapeutic avenues.
517   $aBeyond Borders
606   $aMedicine$2bicssc
610   $aanimal models
610   $abrain imaging
610   $acell models
610   $aCNS involvement
610   $aDM1
610   $aDM2
610   $amultisystemic diseases
610   $amyotonic dystrophy type 1 and type 2
610   $aphenotypes
610   $arepeat disorders
615  7$aMedicine
700   $aSchoser$b Benedikt$4auth$01767366
702   $aMeola$b Giovanni
906   $aBOOK
912   $a9910345962003321
996   $aBeyond Borders: Myotonic Dystrophies - A European Perception$94212515
997   $aUNINA