LEADER 02113nam  2200457z- 450 
001 9910345960903321
005 20231214133514.0
035   $a(CKB)4920000000094105
035   $a(oapen)https://directory.doabooks.org/handle/20.500.12854/59076
035   $a(EXLCZ)994920000000094105
100   $a20202102d2018      |y             0
101 0 $aeng
135   $aurmn|---annan
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aThe Second Life of Natural Killer (NK) Cells
210   $cFrontiers Media SA$d2018
215   $a1 electronic resource (118 p.)
225 1 $aFrontiers Research Topics
311   $a2-88945-546-7 
330   $aNatural Killer (NK) cells are innate lymphocytes, now recognized as members of a larger family of ?Innate lymphoid cells? (ILCs). Both murine and human NK cells are well characterized effector cells with cytotoxic as well as cytokine production ability which mainly react in response to microbial and cell stress stimuli, thus playing a central role in the defense against pathogen infection, in tumor surveillance and in regulating immune homeostasis. Despite these established concepts, our understanding of the complexity of NK cells, also in view of their developmental and functional relationship with other ILC subsets, is only recently emerging. This Research Topic highlights the recent advances in NK cell (and ILC) research in human and mouse from basic research to clinical applications.
517   $aSecond Life of Natural Killer 
610   $anatural killer cells
610   $aILC
610   $aNK cells
610   $aimmune therapy
610   $aviral infection
610   $aNK cell education
610   $aimmunotherapy
610   $aMHC-I
610   $acancer
610   $aimmune regulation
610   $aadaptive immunity
700   $aJoseph C. Sun$4auth$01318561
702   $aMarco Colonna$4auth
702   $aChiara Romagnani$4auth
906   $aBOOK
912   $a9910345960903321
996   $aThe Second Life of Natural Killer (NK) Cells$93033403
997   $aUNINA