LEADER 04066nam 22005775 450 001 9910337604103321 005 20251116215857.0 010 $a3-030-06217-1 024 7 $a10.1007/978-3-030-06217-0 035 $a(CKB)4100000008962855 035 $a(DE-He213)978-3-030-06217-0 035 $a(PPN)242840957 035 $a(EXLCZ)994100000008962855 100 $a20190617d2020 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPeripheral Nerve Tissue Engineering and Regeneration /$fedited by James Phillips, David Hercher, Thomas Hausner 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2020. 225 1 $aTissue Engineering and Regeneration 327 $aBiomaterials -- Natural materials -- Synthetic materials -- Decellularised nerve grafts -- Cells -- Schwann cells -- Therapeutic cells for seeding in nerve repair guides -- Grafts containing live neurons -- Drugs, Gene Therapy and Extracellular Vesicles -- Drugs for enhancing nerve repair -- Gene therapy -- Extracellular vesicle therapies -- Models -- In vitro models -- Appropriate preclinical animal models for translational research -- Mathematical and computational models -- Clinical Translation -- Regulatory considerations -- Manufacturing considerations -- Clinical trials -- Commercialisation of nerve repair technology -- Surgical techniques. 330 $aThis updatable book provides an accessible informative overview of the current state of the art in nerve repair research. The introduction includes history of nerve repair research and establishes key concepts and terminology and will be followed by sections that represent the main areas of interest in the field: (1) Biomaterials, (2) Therapeutic Cells, (3) Drug, Gene and Extracellular Vesicle Therapies, (4) Research Models and (5) Clinical Translation. Each section will contain 3 - 6 chapters, capturing the full breadth of relevant technology. Bringing together diverse disciplines under one overarching theme echoes the multidisciplinary approach that underpins modern tissue engineering and regenerative medicine. Each chapter will be written in an accessible manner that will facilitate interest and understanding, providing a comprehensive single reference source. The updatable nature of the work will ensure that it can evolve to accommodate future changes and new technologies. The main readership for this work will be researchers and clinicians based in academic, industrial and healthcare settings all over the world. 410 0$aTissue Engineering and Regeneration 606 $aBiomedical engineering 606 $aRegenerative medicine 606 $aTissue engineering 606 $aBiomaterials 606 $aNeurosciences 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aBiomaterials$3https://scigraph.springernature.com/ontologies/product-market-codes/Z13000 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 615 0$aBiomedical engineering. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aBiomaterials. 615 0$aNeurosciences. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aRegenerative Medicine/Tissue Engineering. 615 24$aBiomaterials. 615 24$aNeurosciences. 676 $a610.28 702 $aPhillips$b James B.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHercher$b David$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aHausner$b Thomas$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910337604103321 996 $aPeripheral Nerve Tissue Engineering and Regeneration$92871673 997 $aUNINA