LEADER 04309nam 22004935 450 001 9910337533803321 005 20200629192014.0 010 $a3-030-11339-6 024 7 $a10.1007/978-3-030-11339-1 035 $a(CKB)4930000000042108 035 $a(MiAaPQ)EBC5741977 035 $a(DE-He213)978-3-030-11339-1 035 $a(PPN)235232262 035 $a(EXLCZ)994930000000042108 100 $a20190327d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aPituitary Disorders of Childhood $eDiagnosis and Clinical Management /$fedited by Brenda Kohn 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Humana,$d2019. 215 $a1 online resource (362 pages) 225 1 $aContemporary Endocrinology,$x2523-3785 311 $a3-030-11338-8 327 $aPart I. Embryologic and Genetic Disorders of the Pituitary Gland -- Genomics -- Genetics of Hypopituitarism -- Part II. Acquired Pituitary Disorders: Pituitary Tumors and Nonpituitary Sellar Masses -- Adamantinomatous Craniopharyngioma: Genomics, Radiologic Findings, Clinical, Prognosis -- Prolactinomas -- Cushing?s Disease: Diagnosis and Treatment -- Surgery for Cushing?s Disease -- Gigantism and Acromegaly -- TSH Secreting Pituitary Adenomas -- Molecular Predictors of Clinical Behavior in Pituitary Adenohypophysial Tumors -- Nonpituitary Sellar Masses and Infiltrative Disorders -- Part III. Posterior Pituitary Disorders -- Posterior Pituitary Disorders: Anatomy and Physiology; Central Diabetes Insipidus (CDI); Syndrome of Inappropriate Anti-diuretic Hormone (SIADH) -- Part IV. Functional Hypothalamic-Pituitary Hormone Deficiencies -- Congenital Hypogonadotropic Hypogonadism (Isolated GnRH Deficiency) -- Genetics of Delayed Puberty -- Hypothalamic Amenorrhea -- Part V. Neuro-opthalmic Diseases -- Neuro-ophthalmic Diseases and Endocrinologic Function -- Part VI. CNS Radiation -- CNS Radiation of Childhood CNS Tumors -- Part VII. Childhood Cancer Treatment -- Hypothalamic-Pituitary Dysfunction as a Late-Effect of Childhood Cancer, Brain Tumors and their Treatments -- Part VIII. Traumatic Brain Injury -- Pituitary Response to Traumatic Brain Injury. 330 $aThis unique book presents an up-to-date discussion of clinical disorders of the pituitary gland in children with specific emphasis on state-of-the-art diagnostic and treatment modalities, highlighting the newest scientific advances in genomics and molecular biology that clinician-scientists caring for children need to know. Chapters focus on the current knowledge base in genomics, pathophysiology, diagnosis, and medical and surgical management, organized into thematic sections. Part I discusses embryologic and genetic disorders, including genomics and congenital disorders of the pituitary. Part II presents acquired pituitary disorders, such as prolactinomas, Cushing's Disease, and both hormone secreting and non-secreting pituitary tumors. Subsequent sections cover posterior pituitary disorders, such as diabetes insipidus, functional hormone deficiencies of the hypothalamic-pituitary axis, including delayed puberty and pubertal disorders and growth hormone disorders, neuro-opthalmic disease, CNS radiation, childhood cancer treatment and traumatic brain injury. Authoritative and comprehensive, Pituitary Disorders of Childhood will serve as a precise guide for clinical endocrinologists and will guide future investigation into translational and clinical research on the pediatric pituitary. 410 0$aContemporary Endocrinology,$x2523-3785 606 $aEndocrinology  606 $aPediatrics 606 $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053 606 $aPediatrics$3https://scigraph.springernature.com/ontologies/product-market-codes/H49006 615 0$aEndocrinology . 615 0$aPediatrics. 615 14$aEndocrinology. 615 24$aPediatrics. 676 $a616.99247 676 $a616.47 702 $aKohn$b Brenda$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910337533803321 996 $aPituitary Disorders of Childhood$91742357 997 $aUNINA