LEADER 03387nam 22005415 450 001 9910337492703321 005 20200704075532.0 010 $a3-030-00362-0 024 7 $a10.1007/978-3-030-00362-3 035 $a(CKB)4100000007334859 035 $a(DE-He213)978-3-030-00362-3 035 $a(MiAaPQ)EBC5626879 035 $a(PPN)232964513 035 $a(EXLCZ)994100000007334859 100 $a20181227d2019 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAggressive Lymphomas /$fedited by Georg Lenz, Gilles Salles 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (VII, 360 p. 70 illus., 65 illus. in color.) 225 1 $aHematologic Malignancies,$x2197-9766 311 $a3-030-00361-2 327 $aPART I: Epidemiology, Pathology and molecular Pathogenesis: Epidemiology -- Pathology and molecular pathogenesis of DLBCL and related entities -- Pathology and molecular pathogenesis of Burkitt lymphoma and lymphoblastic lymphoma -- Pathology and molecular pathogenesis of T-cell lymphoma -- Part III: Future directions in aggressive lymphomas: Role of modern imaging in aggressive lymphoma -- Kinase inhibitors -- Immunologic approaches -- Other novel targeted therapies -- How biology will help guiding our treatment decisions?. 330 $aThis book summarizes current knowledge of the biology and molecular pathogenesis of aggressive lymphomas and reviews the state of the art in diagnostic and therapeutic strategies. The aim is both to provide the reader with a sound understanding of the very significant progress that has been achieved in the understanding and management of these malignancies over recent years and to facilitate appropriate choice of the therapeutic strategy in individual cases. The assessment of different prognostic parameters are clearly presented in order to permits effective risk stratification that impacts on treatment choice. Recent insights into lymphomagenesis are exemplified and may assist in identifying emerging therapeutic targets. The comprehensive and up-to-date nature of the book will make it an ideal reference for all physicians and researchers interested in lymphoma, including clinicians from various medical specialties, biologists, pathologists, radiologists and nuclear medicine specialist, as well as students. 410 0$aHematologic Malignancies,$x2197-9766 606 $aHematology 606 $aPathology 606 $aImmunology 606 $aHematology$3https://scigraph.springernature.com/ontologies/product-market-codes/H3307X 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 615 0$aHematology. 615 0$aPathology. 615 0$aImmunology. 615 14$aHematology. 615 24$aPathology. 615 24$aImmunology. 676 $a616.15 702 $aLenz$b Georg$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSalles$b Gilles$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910337492703321 996 $aAggressive Lymphomas$91734919 997 $aUNINA