LEADER 05515oam 22004932 450 001 9910328157503321 005 20240110211554.0 010 $a90-04-39119-3 024 7 $a10.1163/9789004391192 035 $a(CKB)4920000000028908 035 $a(nllekb)BRILL9789004391192 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/29504 035 $a(MiAaPQ)EBC31456969 035 $a(Au-PeEL)EBL31456969 035 $a(EXLCZ)994920000000028908 100 $a20181016d2019 uy 0 101 0 $aeng 135 $aurun####uuuua 181 $ctxt$2rdacontent 182 $cn$2rdamedia 183 $2rdacarrier 200 10$aAnimal experimentation $eworking towards a paradigm change /$fedited by Kathrin Herrmann, Kimberley Jayne 205 $a1st ed. 210 $cBrill$d2019 210 1$aLeiden ;$aBoston :$cBrill,$d2019. 215 $a1 online resource 225 0 $aHuman-animal studies,$x1573-4226 ;$vVOLUME 22 311 $a90-04-35618-5 320 $aIncludes bibliographical references and index. 327 $tFront Matter --$tCopyright Page --$tDedication --$tForeword --$tPreface --$tAcknowledgements --$tContributors --$tIntroduction --$tWhy and How to Shift the Paradigm --$tRefinement on the Way Towards Replacement: Are We Doing What We Can? /$rKathrin Herrmann --$tHow to Evaluate the Science of Non-human Animal Use in Biomedical Research and Testing: A Proposed Format for Debate /$rRay Greek and Lisa A. Kramer --$tHow Can the Final Goal of Completely Replacing Animal Procedures Successfully Be Achieved? /$rChristiane Baumgartl-Simons and Christiane Hohensee --$tDisease Prevention with a Plant-based Lifestyle /$rSabina V. Vyas --$tPolitics and Legislation of Animal Experimentation --$tPolitical Campaigning: Where Scientific and Ethical Arguments Meet Public Policy /$rEmily McIvor --$tRethinking the 3Rs: From Whitewashing to Rights /$rCharlotte E. Blattner --$tContesting Animal Experiments through Ethics and Epistemology: In Defense of a Political Critique of Animal Experimentation /$rArianna Ferrari --$tOpenness in Animal Experimentation --$tThe Moral Status of Animal Research Subjects in Industry: A Stakeholder Analysis /$rSarah Kenehan --$tIncreasing the Transparency of Animal Experimentation: An Australian Perspective /$rMonika Merkes and Rob Buttrose --$tWasted Money in United States Biomedical and Agricultural Animal Research /$rJim Keen --$tThe Ethics and Philosophy of Animal Experimentation --$tEthics, Efficacy, and Decision-making in Animal Research /$rLawrence A. Hansen and Kori Ann Kosberg --$tBeyond Plausibility Checks: A Case for Moral Doubt in Review Processes of Animal Experimentation /$rMara-Daria Cojocaru and Philipp von Gall --$tHuman Wrongs in Animal Research: A Focus on Moral Injury and Reification /$rJane Johnson and Anna Smajdor --$tEffectiveness of the Animal Model --$tCritically Evaluating Animal Research /$rAndrew Knight --$tExtrapolation of Animal Research Data to Humans: An Analysis of the Evidence /$rRebecca Ram --$tIs Animal-based Biomedical Research Being Used in Its Original Context? /$rConstança Carvalho , Daniel Alves , Andrew Knight and Luis Vicente --$tThe Scientific Problems with Using Non-Human Animals to Predict Human Response to Drugs and Disease /$rRay Greek and Lisa A. Kramer --$tReplacing Animal Tests to Improve Safety for Humans /$rKathy Archibald , Robert Coleman and Tamara Drake --$tGenetic Modification of Animals: Scientific and Ethical Issues /$rJarrod Bailey --$tAnimal Research for Alzheimer Disease: Failures of Science and Ethics /$rJohn J. Pippin , Sarah E. Cavanaugh and Francesca Pistollato --$tBehavioral Research on Captive Animals: Scientific and Ethical Concerns /$rKimberley Jayne and Adam See --$tAnimal-free Education and Training --$tModernizing Biomedical Training: Replacing Live Animal Laboratories with Human Simulation /$rJohn Pawlowski , David Feinstein , Marie L. Crandall and Shalin Gala --$tHumane Education: The Tool for Scientific Revolution in Brazil /$rVanessa Carli Bones , Rita de Cássia Maria Garcia , Gutemberg Gomes Alves , Rita Leal Paixão , Alexandro Aluísio Rocha , Karynn Capilé and Róber Bachinski --$tThe Paradigm Shift: Advanced Animal-free Approaches --$tRecent Developments in Alternatives to Animal Testing /$rKaty Taylor. 330 $aAnimal experimentation has been one of the most controversial areas of animal use, mainly due to the intentional harms inflicted upon animals for the sake of hoped-for benefits in humans. Despite this rationale for continued animal experimentation, shortcomings of this practice have become increasingly more apparent and well-documented. However, these limitations are not yet widely known or appreciated, and there is a danger that they may simply be ignored. The 51 experts who have contributed to Animal Experimentation: Working Towards a Paradigm Change critically review current animal use in science, present new and innovative non-animal approaches to address urgent scientific questions, and offer a roadmap towards an animal-free world of science. 410 0$aHuman-Animal Studies$v22. 606 $aAnimal experimentation 610 $aEthics & moral philosophy 615 0$aAnimal experimentation. 676 $a179/.4 700 $aHerrmann$b Kathrin$4edt$01739560 702 $aHerrmann$b Kathrin 801 0$bNL-LeKB 801 1$bNL-LeKB 906 $aBOOK 912 $a9910328157503321 996 $aAnimal experimentation$94163608 997 $aUNINA