LEADER 02229nam 2200421z- 450 001 9910317708303321 005 20251017110103.0 010 $a9789535154198 010 $a9535154192 024 7 $a10.5772/60489 035 $a(CKB)4970000000099001 035 $a(OAPEN)627315 035 $a(oapen)https://directory.doabooks.org/handle/20.500.12854/66798 035 $a(Perlego)2024413 035 $a(oapen)doab66798 035 $a(DNLM)1699420 035 $a(EXLCZ)994970000000099001 100 $a20201127d2016 uy | 101 0 $aeng 135 $auuuuu---auuuu 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 00$aNext Generation Sequencing$eAdvances, Applications and Challenges 210 $cIntechOpen$d2016 215 $a1 online resource (464 p.) 311 08$a9789535122401 311 08$a9535122401 330 $aNext generation sequencing (NGS) has surpassed the traditional Sanger sequencing method to become the main choice for large-scale, genome-wide sequencing studies with ultra-high-throughput production and a huge reduction in costs. The NGS technologies have had enormous impact on the studies of structural and functional genomics in all the life sciences. In this book, Next Generation Sequencing Advances, Applications and Challenges, the sixteen chapters written by experts cover various aspects of NGS including genomics, transcriptomics and methylomics, the sequencing platforms, and the bioinformatics challenges in processing and analysing huge amounts of sequencing data. Following an overview of the evolution of NGS in the brave new world of omics, the book examines the advances and challenges of NGS applications in basic and applied research on microorganisms, agricultural plants and humans. This book is of value to all who are interested in DNA sequencing and bioinformatics across all fields of the life sciences. 606 $aMedical genetics$2bicssc 610 $aMedical genetics 615 7$aMedical genetics 700 $aK Kulski$b Jerzy$4edt$01307446 702 $aK Kulski$b Jerzy$4oth 906 $aBOOK 912 $a9910317708303321 996 $aNext Generation Sequencing$93028778 997 $aUNINA