LEADER 03682nam 22004935 450 001 9910311940603321 005 20200705080357.0 010 $a981-10-0077-8 024 7 $a10.1007/978-981-10-0077-5 035 $a(CKB)4100000007598419 035 $a(DE-He213)978-981-10-0077-5 035 $a(MiAaPQ)EBC5675620 035 $a(PPN)235002356 035 $a(EXLCZ)994100000007598419 100 $a20190204d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aLongitudinal Data Analysis $eAutoregressive Linear Mixed Effects Models /$fby Ikuko Funatogawa, Takashi Funatogawa 205 $a1st ed. 2018. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018. 215 $a1 online resource (X, 141 p. 27 illus.) 225 1 $aJSS Research Series in Statistics,$x2364-0057 311 $a981-10-0076-X 327 $aChapter 1. Linear mixed effects model -- Chapter 2. Autoregressive linear mixed effects model -- Chapter 3. Bivariate longitudinal data -- Chapter 4. State-space representation -- Chapter 5. Missing data, time dependent covariate -- Chapter 6. Pretest-Posttest data. 330 $aThis book provides a new analytical approach for dynamic data repeatedly measured from multiple subjects over time. Random effects account for differences across subjects. Auto-regression in response itself is often used in time series analysis. In longitudinal data analysis, a static mixed effects model is changed into a dynamic one by the introduction of the auto-regression term. Response levels in this model gradually move toward an asymptote or equilibrium which depends on covariates and random effects. The book provides relationships of the autoregressive linear mixed effects models with linear mixed effects models, marginal models, transition models, nonlinear mixed effects models, growth curves, differential equations, and state space representation. State space representation with a modified Kalman filter provides log likelihoods for maximum likelihood estimation, and this representation is suitable for unequally spaced longitudinal data. The extension to multivariate longitudinal data analysis is also provided. Topics in medical fields, such as response-dependent dose modifications, response-dependent dropouts, and randomized controlled trials are discussed. The text is written in plain terms understandable for researchers in other disciplines such as econometrics, sociology, and ecology for the progress of interdisciplinary research. 410 0$aJSS Research Series in Statistics,$x2364-0057 606 $aStatistics  606 $aStatistical Theory and Methods$3https://scigraph.springernature.com/ontologies/product-market-codes/S11001 606 $aStatistics for Engineering, Physics, Computer Science, Chemistry and Earth Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/S17020 606 $aStatistics and Computing/Statistics Programs$3https://scigraph.springernature.com/ontologies/product-market-codes/S12008 615 0$aStatistics . 615 14$aStatistical Theory and Methods. 615 24$aStatistics for Engineering, Physics, Computer Science, Chemistry and Earth Sciences. 615 24$aStatistics and Computing/Statistics Programs. 676 $a519.5 700 $aFunatogawa$b Ikuko$4aut$4http://id.loc.gov/vocabulary/relators/aut$0767988 702 $aFunatogawa$b Takashi$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910311940603321 996 $aLongitudinal Data Analysis$92163214 997 $aUNINA