LEADER 04568nam 22006975 450 001 9910311936103321 005 20200704065124.0 010 $a3-319-89315-7 024 7 $a10.1007/978-3-319-89315-0 035 $a(CKB)4100000007656806 035 $a(DE-He213)978-3-319-89315-0 035 $a(MiAaPQ)EBC5716635 035 $a(PPN)235005126 035 $a(EXLCZ)994100000007656806 100 $a20190218d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aVasculopathies$b[electronic resource] $eBehavioral, Chemical, Environmental, and Genetic Factors /$fby Marc Thiriet 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (XXXIII, 888 p. 6 illus.) 225 1 $aBiomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems,$x2193-1682 ;$v8 311 $a3-319-89314-9 327 $aPreface -- Cardiovascular Risk Markers -- Hypertension -- Hyperglycemia and Diabetes -- Hyperlipidemias and Obesity -- Behavioral Risk Factors. 330 $aThis volume presents one of the clinical foundations of vasculopathies: the biological markers and risk factors associated with cardiovascular disease. A detailed biological and clinical framework is provided as a prerequisite for adequate modeling. Chapter 1 presents cardiovascular risk factors and markers, where the search for new criteria is aimed at improving early detection of chronic diseases. The subsequent chapters focus on hypertension, which involves the kidney among other organs as well as many agents, hyperglycemia and diabetes, hyperlipidemias and obesity, and behavior. The last of these risk factors includes altered circadian rhythm, tobacco and alcohol consumption, physical inactivity, and diet. The volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in anatomical conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning in quantitative terms. 410 0$aBiomathematical and Biomechanical Modeling of the Circulatory and Ventilatory Systems,$x2193-1682 ;$v8 606 $aBiophysics 606 $aBiological physics 606 $aBiomedical engineering 606 $aBiomathematics 606 $aSystems biology 606 $aFluid mechanics 606 $aCardiology 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aMathematical and Computational Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/M31000 606 $aSystems Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L15010 606 $aEngineering Fluid Dynamics$3https://scigraph.springernature.com/ontologies/product-market-codes/T15044 606 $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aBiomedical engineering. 615 0$aBiomathematics. 615 0$aSystems biology. 615 0$aFluid mechanics. 615 0$aCardiology. 615 14$aBiological and Medical Physics, Biophysics. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aMathematical and Computational Biology. 615 24$aSystems Biology. 615 24$aEngineering Fluid Dynamics. 615 24$aCardiology. 676 $a571.4 700 $aThiriet$b Marc$4aut$4http://id.loc.gov/vocabulary/relators/aut$0791327 906 $aBOOK 912 $a9910311936103321 996 $aVasculopathies$92511526 997 $aUNINA