LEADER 05064nam 22006015 450 001 9910309857803321 005 20230810163411.0 010 $a3-030-01198-4 024 7 $a10.1007/978-3-030-01198-7 035 $a(CKB)4100000007389476 035 $a(DE-He213)978-3-030-01198-7 035 $a(MiAaPQ)EBC5629353 035 $a(EXLCZ)994100000007389476 100 $a20190104d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiological Robustness $eEmerging Perspectives from within the Life Sciences /$fedited by Marta Bertolaso, Silvia Caianiello, Emanuele Serrelli 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (X, 258 p. 26 illus., 15 illus. in color.) 225 1 $aHistory, Philosophy and Theory of the Life Sciences,$x2211-1956 ;$v23 311 $a3-030-01197-6 327 $a1. Introduction: Is Biological Robustness Unique? -- 2. Robustness, Mechanism, and the Counterfactual use of Goal-directedness in Biology (Marco Buzzoni) -- 3. Difference (Alfredo Marcos) -- 4. Robustness and Autonomy (Alvaro Moreno) -- 5. Robustness as an Explanandum and Explanans in Evolutionary Biology and Ecology (Philippe Hunemann) -- 6. Issues in Developmental Robustness (Manfred D. Laubichler) -- 7. Physical Robustness and Biological Robustness: Dynamical Rearrangement of Symmetry and Minimum Stimulus (Giuseppe Vitiello) -- 8. News from the ?Twilight Zone?: Protein Molecules Between the Crystal and the Fluid (Alessandro Giuliani) -- 9. Robustness and Emergent Dynamics in Noisy Biological Systems (Simonetta Filippi) -- 10. Robustness in Neurological Systems (Sandra D. Mitchell) -- 11. Robustness Notions and Physiological Adaptability: Philosophical and Biomedical Reflections on the Neurological Basis of Disorders (Raffaella Campaner) -- 12. Reconciling Variability with Robust Behavior at Single-neuron Level (Timothy O?Leary) -- 13. Functional Connectivity, Regulation, and SOM Interneurons Spontaneous Activity (Alison Barth) -- 14. Temporal Organization and Robustness in Neural Systems (Trey Boone) -- 15. Muscle Synergies: Concept, Principles, and Potential use in Neurorehabilitation Module (Emilio Bizzi) -- 16. Robustness of Musical Language: The Role of Motor Systems (Flavio Keller) -- 17. Conclusion - The Upcoming Role of Robustness in Biology. . 330 $aThis volume reviews examples and notions of robustness at several levels of biological organization. It tackles many philosophical and conceptual issues and casts an outlook on the future challenges of robustness studies in the context of a practice-oriented philosophy of science. The focus of discussion is on concrete case studies. These highlight the necessity of a level-dependent description of robust biological behaviors.Experts from the neurosciences, biochemistry, ecology, biology, and the history and the philosophy of life sciences provide a multiplex perspective on the topic. Contributions span from protein folding, to cell-level robustness, to organismal and developmental robustness, to sensorimotor systems, up to the robustness of ecological systems.Several chapters detail neurobiological case-studies. The brain, the poster child of plasticity in biology, offers multiple examples of robustness. Neurobiology explores the importance of temporal organization and multiscalarity in making this robustness-with-plasticity possible. The discussion also includes structures well beyond the brain, such as muscles and the complex feedback loops involved in the peculiar robustness of music perception. Overall, the volume grounds general reflections upon concrete case studies, opening to all the life sciences but also to non-biological and bio-inspired fields such as post-modern engineering. It will appeal to researchers, students, as well as non-expert readers. 410 0$aHistory, Philosophy and Theory of the Life Sciences,$x2211-1956 ;$v23 606 $aBiology$xPhilosophy 606 $aBioinformatics 606 $aNeurosciences 606 $aPhilosophy of nature 606 $aPhilosophy of Biology 606 $aComputational and Systems Biology 606 $aNeuroscience 606 $aPhilosophy of Nature 615 0$aBiology$xPhilosophy. 615 0$aBioinformatics. 615 0$aNeurosciences. 615 0$aPhilosophy of nature. 615 14$aPhilosophy of Biology. 615 24$aComputational and Systems Biology. 615 24$aNeuroscience. 615 24$aPhilosophy of Nature. 676 $a570.1 676 $a572.838 702 $aBertolaso$b Marta$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aCaianiello$b Silvia$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSerrelli$b Emanuele$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910309857803321 996 $aBiological Robustness$92218325 997 $aUNINA