LEADER 01311nam0-22003731i-450- 001 990004327930403321 005 20110408141904.0 010 $a90-04-09201-3$bset 010 $a90-04-09199-8$bvol. 1 010 $a90-04-09200-5$bvol. 2 035 $a000432793 035 $aFED01000432793 035 $a(Aleph)000432793FED01 035 $a000432793 100 $a19990604d1990----km-y0itay50------ba 101 0 $ager$alat 105 $ay-------001yy 200 1 $a<>Gesta militum des Hugo von Mâcon$eein bisher unbekanntes Werk der Erzählliteratur des Hochmittelalters$fhrsg. von Ewald Könsgen 210 $aLeiden [ecc.]$cBrill$d1990 215 $a2 v.$d23 cm 225 1 $aMittellateinische Studien und Texte$v18 327 1 $a1.: Einleitung und Text$a2.: Auszüge aus dem Kommentar des Guido de Grana 500 10$aDe militum gestis memorabilibus$921885 676 $a873.03 700 1$aHugo:$cMatisconensis$f<1151>$0172518 702 1$aKönsgen,$bEwald 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990004327930403321 952 $aP2B-650-HUGO MAT.-402A(1)-1990$bBibl.8886$fFLFBC$mBRAU-13739 952 $aP2B-650-HUGO MAT.-402A(2)-1990$bBibl.8886$fFLFBC$mBRAU-13740 959 $aFLFBC 996 $aDe militum gestis memorabilibus$921885 997 $aUNINA LEADER 03907nam 22006255 450 001 9910303444103321 005 20200706054921.0 010 $a3-030-03556-5 024 7 $a10.1007/978-3-030-03556-3 035 $a(CKB)4100000007181304 035 $a(MiAaPQ)EBC5611143 035 $a(DE-He213)978-3-030-03556-3 035 $a(PPN)232964963 035 $a(EXLCZ)994100000007181304 100 $a20181205d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aSurface Enhanced Raman Spectroscopy for Biophysical Applications $eUsing Plasmonic Nanoparticle Assemblies /$fby Claudia Fasolato 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (167 pages) 225 1 $aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 311 $a3-030-03555-7 327 $aIntroduction -- Traditional Raman and SERS: fundamentals and state of the art -- Investigation on nanoparticles and their molecular functionalization -- Nanoparticle-based SERS substrates for molecular sensing applications -- SERS-active nanovectors for single-cell cancer screening and theranostics -- Conclusions. 330 $aThe book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications are the goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field. 410 0$aSpringer Theses, Recognizing Outstanding Ph.D. Research,$x2190-5053 606 $aSpectrum analysis 606 $aMicroscopy 606 $aBiophysics 606 $aBiophysics 606 $aSurfaces (Physics) 606 $aInterfaces (Physical sciences) 606 $aThin films 606 $aSpectroscopy and Microscopy$3https://scigraph.springernature.com/ontologies/product-market-codes/P31090 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aSurface and Interface Science, Thin Films$3https://scigraph.springernature.com/ontologies/product-market-codes/P25160 615 0$aSpectrum analysis. 615 0$aMicroscopy. 615 0$aBiophysics. 615 0$aBiophysics. 615 0$aSurfaces (Physics) 615 0$aInterfaces (Physical sciences) 615 0$aThin films. 615 14$aSpectroscopy and Microscopy. 615 24$aBiological and Medical Physics, Biophysics. 615 24$aSurface and Interface Science, Thin Films. 676 $a535.846 700 $aFasolato$b Claudia$4aut$4http://id.loc.gov/vocabulary/relators/aut$01063734 906 $aBOOK 912 $a9910303444103321 996 $aSurface Enhanced Raman Spectroscopy for Biophysical Applications$92534280 997 $aUNINA