LEADER 04461nam 22005895 450 001 9910303436603321 005 20231110193709.0 010 $a3-319-97110-7 024 7 $a10.1007/978-3-319-97110-0 035 $a(CKB)4100000007204894 035 $a(DE-He213)978-3-319-97110-0 035 $a(MiAaPQ)EBC6298232 035 $a(PPN)232963134 035 $a(EXLCZ)994100000007204894 100 $a20181206d2018 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNew Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins /$fedited by Bob Kiss, Uwe Gottschalk, Michael Pohlscheidt 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (VI, 469 p. 70 illus., 54 illus. in color.) 225 1 $aAdvances in Biochemical Engineering/Biotechnology,$x0724-6145 ;$v165 311 $a3-319-97108-5 327 $aMarket and Capacity evolvement of the Biopharmaceutical Industry -- New Mammalian Expression Systems -- Innovation in seed train cultivation and production culture -- Manufacturing of Proteins and Antibodies / Risk mitigation for the contamination by adventitious agents -- Harvest operations -- Downstream Processing Technologies / Capturing and Final Purifaction -- Fully disposable manufacturing concepts for clinical and commercial manufacturing and Ballroom Concepts -- Augmented Reality ? PAT and Artificial Intelligence for innovative process monitoring and controls -- Trends and innovations in formulations, fill and finish technologies and drug delivery -- Process Integration towards continuous manufacturing -- Future direction of Manufacturing of novel molecular format - a research perspective (bispecific antibodies, ADC, Ab fragments, fusion proteins, etc -- Cell therapy manufacturing for modern therapeutics -- Gene therapy -- Modern technologies and strategies for vaccine manufacturing -- Product and Technology Lifecycle Management in the Pharmaceutical Industry -- Integrated High Throughput Development -- A different perspective ? How much innovation is really needed for production of mAb by mammalian cell technology? 330 $aThis book review series presents current trends in modern biotechnology. The aim is to cover all aspects of this interdisciplinary technology where knowledge, methods and expertise are required from chemistry, biochemistry, microbiology, genetics, chemical engineering and computer science. Volumes are organized topically and provide a comprehensive discussion of developments in the respective field over the past 3-5 years. The series also discusses new discoveries and applications. Special volumes are dedicated to selected topics which focus on new biotechnological products and new processes for their synthesis and purification. In general, special volumes are edited by well-known guest editors. The series editor and publisher will however always be pleased to receive suggestions and supplementary information. Manuscripts are accepted in English. 410 0$aAdvances in Biochemical Engineering/Biotechnology,$x0724-6145 ;$v165 606 $aBiotechnology 606 $aPharmaceutical technology 606 $aMedicinal chemistry 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 606 $aMedicinal Chemistry$3https://scigraph.springernature.com/ontologies/product-market-codes/C28000 615 0$aBiotechnology. 615 0$aPharmaceutical technology. 615 0$aMedicinal chemistry. 615 14$aBiotechnology. 615 24$aPharmaceutical Sciences/Technology. 615 24$aMedicinal Chemistry. 676 $a660.6 702 $aKiss$b Bob$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGottschalk$b Uwe$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aPohlscheidt$b Michael$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910303436603321 996 $aNew Bioprocessing Strategies: Development and Manufacturing of Recombinant Antibodies and Proteins$91568699 997 $aUNINA