LEADER 04275nam 22005775 450 001 9910300457003321 005 20200705022643.0 010 $a88-470-3955-X 024 7 $a10.1007/978-88-470-3955-1 035 $a(CKB)4100000000882265 035 $a(DE-He213)978-88-470-3955-1 035 $a(MiAaPQ)EBC5104261 035 $a(PPN)220121915 035 $a(EXLCZ)994100000000882265 100 $a20171013d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAbdominal Neuroendocrine Tumors /$fedited by Massimo Carlini 205 $a1st ed. 2018. 210 1$aMilano :$cSpringer Milan :$cImprint: Springer,$d2018. 215 $a1 online resource (Approx. 200 p. 20 illus., 10 illus. in color.) 225 1 $aUpdates in Surgery,$x2280-9848 311 $a88-470-3954-1 320 $aIncludes bibliographical references. 327 $aForeword -- Preface -- 1 Anatomophysiology of the neuroendocrine system: Embryology, Anatomy ? Histology ? Citology, Physiology -- 2 Epidemiology: Risk factors -- 3 Classification: WHO (grading), site -- 4 Pathology: Anatomic pathology, Immunohistochemistry. ? 5 Molecular biology: Molecular pathways, Oncogenes, Suppressor genes -- 6 Clinical presentations: Non functioning NETs -- 7 Clinical presentations: Hormone releasing NETs (Carcinoid syndrome, Insulinoma, Glucagonoma, VIPoma, Somatostatinoma, Others, GRFoma -- 8 MEN 1, MEN 2am, MEN 2b, and Others (TSC, VHL, NF1) -- 9 Diagnosis: (Serum biomarkers, Endoscopy, Imaging (US, CT Scan, MRI, Angiography, Scintigraphy, PET) -- 10 Staging: TNM -- 11 Surgical treatment: Gastric NETs, Duodenum NETs, Jejuno-ileal NETs, Colorectal NETs, Pancreatic NETs (Head, Body-tail), Adrenal NETs -- 12 Non surgical treatments: Chemotherapy, Hormonal syndrome treatment, Targeted therapies, IFN -- 13 Metastatic disease: Liver metastases (Surgery, RF ablation and cryoablation, Arterial chemoembolization) -- 14 Systemic therapy (Somatostatina analogs, Alpha IFN, Cytotoxic chemotherapy, Peptide receptor radiotherapy, VEGF inhibitors, mTOR inhibitors -- 15 Flow-charts. 330 $aThis book aims to equip readers with a better understanding of neuroendocrine tumors of the abdomen and explains how to manage them optimally by making use of novel therapeutic options that represent major advances on previous treatments. The most recent advances in epidemiology, genetics, molecular biology, biomarkers, pathology, diagnostics, clinical assessment, medical therapy, and surgical treatment are presented. The information and data provided will stimulate readers to develop their personal opinions on significant issues and assist in decision making in individual patients during routine clinical practice. The book features a multidisciplinary approach and is designed to meet the needs of all physicians seeking comprehensive guidance from experts on the management of patients with neuroendocrine tumors. It will also be of value for researchers wishing to acquaint themselves with the state of the art in the field and emerging research avenues. Abdominal Neuroendocrine Tumors is published in Springer?s highly successful Updates in Surgery series, which now comprises more than 20 titles. 410 0$aUpdates in Surgery,$x2280-9848 606 $aAbdominal surgery 606 $aSurgical oncology 606 $aEndocrinology  606 $aAbdominal Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H5901X 606 $aSurgical Oncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H59150 606 $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053 615 0$aAbdominal surgery. 615 0$aSurgical oncology. 615 0$aEndocrinology . 615 14$aAbdominal Surgery. 615 24$aSurgical Oncology. 615 24$aEndocrinology. 676 $a616.99437 702 $aCarlini$b Massimo$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910300457003321 996 $aAbdominal Neuroendocrine Tumors$91742326 997 $aUNINA