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010   $a3-319-68582-1
024 7 $a10.1007/978-3-319-68582-3
035   $a(CKB)4100000001795033
035   $a(DE-He213)978-3-319-68582-3
035   $a(MiAaPQ)EBC5217062
035   $a(PPN)223957801
035   $a(EXLCZ)994100000001795033
100   $a20180109d2018      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aTumor Deposits $eMechanism, Morphology and Prognostic Implications /$fby Sulen Sarioglu
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018.
215   $a1 online resource (XIV, 189 p. 136 illus. in color.) 
311   $a3-319-68581-3 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aMechanisms of Metastasis -- Free Tumor Deposits (FTD); Mechanisms, Morphology and Differential Diagnosis -- Tumor Deposits in Colorectal Cancer -- Tumor Deposits in Gastric Cancer -- Tumor Deposits in Esophageal Carcinomas -- Peritoneal Carcinomatosis-Relation to Tumor Deposits -- Tumor Deposts in Salivary Gland Carcinomas -- Tumor Deposits in Head and Neck Tumors -- Tumor Deposits in Breast Carcinomas.
330   $aThis book presents the morphology, possible mechanisms of formation, and clinical relevance of tumor deposits (TDs) in different organs and parts of the body. It also describes the diagnostic features that are currently available for TDs and discusses the prognostic impact of TDs. The poor prognostic and predictive values of TDs were found to be as strong as distant metastasis in different series.  TDs, best characterized by colorectal cancer, are irregular discrete tumor masses that are discontinuous from the leading edge of the tumor. However, even in colorectal cancers, the place of TDs in tumor staging (tumor, lymph node and distant metastasis categories) remains controversial. This book presents the possible mechanisms of TD formation, including neurotrophic and angiotrophic extravascular migratory metastasis, in comparison with the well-known mechanisms of metastasis. It also shows that TDs were identified in esophageal, gastric, salivary gland, head and neck, and breast carcinomas. The possible mechanisms leading to the frequent association of TDs and peritoneal carcinomatosis are discussed.  This is a valuable resource for pathologists, oncologists, and surgeons who are looking for detailed information on the latest scientific insights into the pathology and prognostic implications of TDs.
606   $aPathology
606   $aOncology  
606   $aSurgery
606   $aOtolaryngologic surgery
606   $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X
606   $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160
606   $aGeneral Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59044
606   $aHead and Neck Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H46015
615  0$aPathology.
615  0$aOncology  .
615  0$aSurgery.
615  0$aOtolaryngologic surgery.
615 14$aPathology.
615 24$aOncology.
615 24$aGeneral Surgery.
615 24$aHead and Neck Surgery.
676   $a616.07
700   $aSarioglu$b Sulen$4aut$4http://id.loc.gov/vocabulary/relators/aut$0788108
906   $aBOOK
912   $a9910300437703321
996   $aTumor Deposits$91756592
997   $aUNINA