LEADER 10121nam 22008535 450 001 9910300355703321 005 20200701123247.0 010 $a0-387-84828-2 024 7 $a10.1007/978-0-387-84828-0 035 $a(CKB)3710000000249661 035 $a(SSID)ssj0001354116 035 $a(PQKBManifestationID)11705814 035 $a(PQKBTitleCode)TC0001354116 035 $a(PQKBWorkID)11322679 035 $a(PQKB)10492330 035 $a(DE-He213)978-0-387-84828-0 035 $a(MiAaPQ)EBC6311474 035 $a(MiAaPQ)EBC5584554 035 $a(Au-PeEL)EBL5584554 035 $a(OCoLC)1048163784 035 $a(PPN)181345706 035 $a(EXLCZ)993710000000249661 100 $a20140909d2014 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aEncyclopedia of Medical Immunology $eAutoimmune Diseases /$fedited by Ian R. Mackay, Noel R. Rose, Betty Diamond, Anne Davidson 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (227 illus., 179 illus. in color. eReference.) 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a0-387-84829-0 311 $a0-387-84827-4 320 $aIncludes bibliographical references. 327 $aB cell development and repertoire sel: B cell central tolerance: controlling self-reactive B cells in the bone marrow -- B cell tolerance -- B cell trafficking -- B1 cells -- BCR signaling -- CS and SHM -- MZB cells -- Plasma Cells -- Regulatory B cells -- Repertoire selection -- TFH help -- Cardiovascular/systemic inflammation: Atherosclerosis and cytokines.-Autoantibodies and atherosclerosis -- Autoantibodies to endothelial cells -- Autoimmune disease and premature atherosclerosis -- Autoimmune heart disease animal models -- Autoimmune myocarditis and pericarditis -- Cell adhesion molecules -- Dendritic cells and atherosclerosis -- Endothelial cells and inflammation -- Immune mediated mechanisms of the metabolic syndrome -- Lymphocytes in Atherosclerosis -- Macrophages, Oxidative stress and Atherosclerosis -- Mechanisms of endothelial activation -- Neutrophils in endothelial damage -- Platelets, atherosclerosis and immunity -- Viral myocarditis -- Gut: Celiac disease -- Overview of the Gut microbiome -- Overview on IBD -- Overview on mucosal immunity -- Liver: Adaptive immune cells in the liver -- AIH: clinical + systemic manifestations and treatment -- AIH: Pathogenesis, association with other syndromes -- Animal models of AIH -- Animal models of hepatitis B and C -- Gestational Alloimmune Liver Disease -- Immune response during acute and chronic Hepatitis B -- Immune response during acute and chronic Hepatitis C -- Immunosuppression in clinical liver transplantation -- Innate immune cells in the liver -- KC and tolerance -- Liver transplantation tolerance in animal models -- Liver vasculature and microvasculature -- LSEC and tolerance -- PBC genetics -- PBC: clinical + systemic manifestations and treatment -- Primary T Cell activation in the liver -- PSC: clinical + systemic manifestations and treatment -- The hepatic lymphatic system -- Transplantation for auto immune diseases -- Transplantation for chronic viral hepatitis -- Tregs in the liver -- Ultrastructure of the liver sinusoid -- Lymphocytes activation T, B, NK: B7/CD28 family -- Bcl-2 family -- CD40 -- CD5 -- Chemokines -- CTLA4-Ig -- Cytotoxic T cells -- FcRIIb -- GTPases -- IL-21 -- Interleukin 6 -- LAT -- mTOR -- NFAT -- NFkB -- NK cell activation -- PI3K -- PKCtheta -- PTPN22 -- Rho/Rac GTPases -- SHIP -- T cell memory -- Paraneoplastic: Cancer and dermatomyositis -- Cancer and Fever -- Cancer and joint pain -- Cancer and nephrotic syndrome -- Cancer and neuropathies -- Cancer and the CNS -- Cancer and thrombosis -- Cancer therapies and autoimmunity -- Paraneoplastic Syndromes, an overview -- Tumor Infiltrating T cells -- Tumor Macrophages -- Resolution of Inflammation: Anti-oxidants -- CD5 -- CTLA 4 -- EICOSANOIDS (prostaglandins, leucotrienes, and related compounds) -- Fas/fas ligand -- Fibrosis -- Nitric oxide -- Polymorphonuclear Leucocytes (PMN)/neutrophils -- Resolution of Inflammation -- TGFbeta -- Kidney: Anti-GBM GN -- Autoimmune disease -- Autoimmune Kidney Disease and Pregnancy -- Autoimmunity and Inflammation in Diabetic Nephropathy -- Complement regulation in the Kidney -- IgA Nephropathy -- Immune System and the Kidney -- Impact of Recurrent Autoimmune Diseases in Renal Transplant Outcomes -- Indications for Biopsy in Autoimmune GN -- Pathogenesis of Lupus Nephritis and New Approaches to Treatment -- Proteinuric Kidney Diseases: Importance of Blood Pressure Control -- Scleroderma Renal Crisis -- Spectrum of Minimal Change Disease to Focal Segmental Glomerulosclerosis -- Translational aspects of MN -- TTP and the Kidney -- Vasculitits and the Kidney (ANCA, etc) -- Regulatory lymphocytes T, B, other: Regulatory B cells -- Tregs: Regulatory T cells -- Rheumatic Disease: APLS- Mechanism of thrombosis -- APLS- treatment -- APLS-Clinical Manifestations -- Autoinflammatory Syndromes -- Complement in rheumatic diseases -- Diagnosis and Treatment of Lupus Nephritis -- Environment and autoimmunity -- Epigenetics in autoimmunity -- Immunodeficiency in Autoimmune diseases -- Juvenile diseases: Arthritis treatment in children (incl. pathogenesis, presentation & treatment) -- Juvenile diseases: Genetics of JIA -- Juvenile diseases: Juvenile arthritis syndromes -- Juvenile diseases: Kawasaki syndrome -- Juvenile diseases: SLE-children -- microRNA in autoimmunity -- Myositis pathogenesis -- Myositis-Dermatomyositis, Polymyositis, inclusion body myositis, and autoantibodies -- Myositis: Juvenile myositis -- Nephritogenic autoantibodies in SLE -- RA- clinical features -- RA- extraarticular manifestations -- RA-animal models -- RA-autoantibodies -- RA-genetics -- RA-treatment -- RA: Biologics in the treatment of RA -- RA: Small molecules -- Raynauds phenomenon -- Sarcoidosis -- Scleroderma-genetics -- Scleroderma: Pathogenesis and Clinical Manifestations -- Sjogren's syndrome -- SLE - Clinical Trials in SLE -- SLE - Discoid SLE -- SLE - Novel targets in SLE Essay -- SLE-animal models -- SLE-autoantibodies -- SLE-clinical features and diagnosis -- SLE-gender and hormonal influences -- SLE-genetics -- SLE-pathogenesis -- SLE-pregnancy -- SLE-skin -- SLE-treatment -- SLE: Congenital heart block and neonatal lupus -- SLE: Mixed connective tissue disease (MCTD) -- Spondyloarthritis: Ankylosing Spondylitis -- Spondyloarthritis: Psoriatic arthritis -- Spondyloarthritis: Reactive Arthritis -- Treatment (current and upcoming) of scleroderma -- Vasculitis: Bechets -- Vasculitis: Churg-Strauss syndrome.-Vasculitis: Cutaneous vasculitis (hypersensitivity vasculitis) -- Vasculitis: Giant cell arteritis.-Vasculitis: Henoch-Schonlein purpura -- Vasculitis: Microscopic polyangiitis -- Vasculitis: Polyarteritis nodosa -- Vasculitis: Polymyalgia rheumatica -- Vasculitis: Primary CNS vasculitis.-Vasculitis: Wegenerâ??s granulomatosis -- Skin and Alopecia: Alopecia areata -- Autoimmune Blistering Diseases -- Blistering diseases: Bullous Pemphigoid -- Blistering diseases: Mucous Membrane Pemphigoid -- Blistering diseases: Linear IgA disease (LAD) -- Blistering diseases: Pemphigus -- Dermatomyositis -- Erythema nodosum -- Hair Loss In Lupus Erythematosus -- Inflammatory - SLE ? Skin -- Inflammatory: Dermatomyositis ? skin -- Inflammatory: Discoid lupus -- Inflammatory: psoriasis cutaneous -- Lichen Planopilaris -- Lichen planus -- Neutrophilic dermatoses: Sweets syndrome -- Neutrophilic dermatoses: Leukocytoclastic vasculitis -- Neutrophilic dermatoses: Pyoderma gangrenosum -- Scleroderma like conditions -- Skin and Alopecia -- Vitiligo. 330 $aDifferent from other resources, this volume offers a broad appeal to microbiologists, immunologists, and infectious disease specialists on Autoimmune Diseases. The volume covers topics such as skin and alopecia, Kidney, Liver, Paraneoplastic, Resolution of inflammation, Cardiovascular/systemic inflammation and atherosclerosis, Gut, Regulatory lymphocytes T, B, other and Rheumatic Disease. The volume is written by internationally renowned authors who are authorities in their respective fields. 606 $aInfectious diseases 606 $aImmunology 606 $aMedical microbiology 606 $aVirology 606 $aPharmacology 606 $aPublic health 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aMedical Microbiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B16003 606 $aVirology$3https://scigraph.springernature.com/ontologies/product-market-codes/B22003 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aPublic Health$3https://scigraph.springernature.com/ontologies/product-market-codes/H27002 615 0$aInfectious diseases. 615 0$aImmunology. 615 0$aMedical microbiology. 615 0$aVirology. 615 0$aPharmacology. 615 0$aPublic health. 615 14$aInfectious Diseases. 615 24$aImmunology. 615 24$aMedical Microbiology. 615 24$aVirology. 615 24$aPharmacology/Toxicology. 615 24$aPublic Health. 676 $a616.978 702 $aMackay$b Ian R$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRose$b Noel R$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDiamond$b Betty$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDavidson$b Anne$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910300355703321 996 $aEncyclopedia of Medical Immunology$91520325 997 $aUNINA