LEADER 03130nam 22006255 450 001 9910300354803321 005 20200704082037.0 010 $a1-907673-67-9 024 7 $a10.1007/978-1-907673-67-2 035 $a(CKB)3710000000119073 035 $a(EBL)1782077 035 $a(SSID)ssj0001244516 035 $a(PQKBManifestationID)11730377 035 $a(PQKBTitleCode)TC0001244516 035 $a(PQKBWorkID)11312596 035 $a(PQKB)10404355 035 $a(MiAaPQ)EBC1782077 035 $a(DE-He213)978-1-907673-67-2 035 $a(PPN)178779296 035 $a(EXLCZ)993710000000119073 100 $a20140529d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aManaging Gout in Primary Care /$fby Fernando Perez-Ruiz, Ana Maria Herrero-Beites 205 $a1st ed. 2014. 210 1$aTarporley :$cSpringer Healthcare Ltd. :$cImprint: Springer Healthcare,$d2014. 215 $a1 online resource (78 p.) 300 $aDescription based upon print version of record. 311 $a1-322-13340-9 311 $a1-907673-66-0 320 $aIncludes bibliographical references at the end of each chapters. 327 $aDisease Overview -- Physiopathology of Gout -- Diagnosis of Gout -- Treatment of Hyperuricemia in Gout -- Prevention and Treatment of Inflammation in Gout -- Appendix. 330 $aThis handbook discusses developments and the future of gout treatment, which looks promising. Gout has been a well-known disease for over 2000 years, and is the most common cause of joint inflammation in adult males. It has become apparent that no therapeutic target based on hyperuricemia outcome had been defined. Very few controlled trials were available to test the efficacy and safety of treatments, and no research on diagnosis and management had been done despite data showing that patients with gout were generally improperly treated even in the hands of specialists. In the last 10 years, good-quality evidence on gout impact and management has grown exponentially, renal transporters have been recently identified, and a number of new drugs have been approved or are under current development. 606 $aRheumatology 606 $aPharmacotherapy 606 $aOrthopedics 606 $aRheumatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33170 606 $aPharmacotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H69000 606 $aOrthopedics$3https://scigraph.springernature.com/ontologies/product-market-codes/H45000 615 0$aRheumatology. 615 0$aPharmacotherapy. 615 0$aOrthopedics. 615 14$aRheumatology. 615 24$aPharmacotherapy. 615 24$aOrthopedics. 676 $a616.3999 700 $aPerez-Ruiz$b Fernando$4aut$4http://id.loc.gov/vocabulary/relators/aut$0755333 702 $aHerrero-Beites$b Ana Maria$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910300354803321 996 $aManaging Gout in Primary Care$92523327 997 $aUNINA