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010   $a3-642-54687-0
024 7 $a10.1007/978-3-642-54687-7
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035   $a(OCoLC)890981480
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035   $a(EXLCZ)993710000000129320
100   $a20140616d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aClinical Neuroembryology $eDevelopment and Developmental Disorders of the Human Central Nervous System /$fby Hans J. ten Donkelaar, Martin Lammens, Akira Hori
205   $a2nd ed. 2014.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014.
215   $a1 online resource (675 p.)
300   $aDescription based upon print version of record.
311   $a1-322-13914-8 
311   $a3-642-54686-2 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aOverview of the Development of the Human Brain and Spinal Cord -- Mechanisms of Development -- Causes of Congenital Malformations -- Neurulation and Neural tube Defects -- The Neural Crest and Craniofacial Malformations -- Development and Developmental Disorders of the Spinal Cord -- Development and Developmental Disorders of the Brain Stem -- Development and Developmental Disorders of the Human Cerebellum -- Development and Developmental Disorders of the Forebrain -- Development and Developmental Disorders of the Cerebral Cortex.
330   $aThis book provides a comprehensive overview of the development of the human central nervous system (CNS) in the context of its many developmental disorders due to genetic, environmental, and hypoxic/ischemic causes. The introductory chapters give an overview of the development of the human brain and the spinal cord, the mechanisms of development as obtained in experimental studies of various invertebrates and vertebrates, and  the causes of congenital malformations. In the main part, the developmental disorders of the human brain and the spinal cord are presented in a regional, more or less segmental way, starting with neurulation and neural tube defects, and ending with developmental disorders of the cerebral cortex. These are underlined by carefully chosen clinical case studies, including imaging data and, when available, postmortem verification of the developmental disorders involved. Numerous color photographs and illustrations complement the text. This second edition emphasizes the prenatal diagnosis by ultrasound, MRI, and DTI and implements new classifications of developmental disorders.
606   $aNeurology 
606   $aNeurosciences
606   $aHuman genetics
606   $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001
606   $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
615  0$aNeurology .
615  0$aNeurosciences.
615  0$aHuman genetics.
615 14$aNeurology.
615 24$aNeurosciences.
615 24$aHuman Genetics.
676   $a599.935
676   $a599935
676   $a610
676   $a611.01816
700   $aten Donkelaar$b Hans J$4aut$4http://id.loc.gov/vocabulary/relators/aut$0897748
702   $aLammens$b Martin$4aut$4http://id.loc.gov/vocabulary/relators/aut
702   $aHori$b Akira$4aut$4http://id.loc.gov/vocabulary/relators/aut
906   $aBOOK
912   $a9910300354503321
996   $aClinical Neuroembryology$92519595
997   $aUNINA