LEADER 07052nam 22007455 450 001 9910300343603321 005 20200706172418.0 010 $a1-4939-0265-2 024 7 $a10.1007/978-1-4939-0265-1 035 $a(CKB)3710000000125599 035 $a(EBL)1782006 035 $a(SSID)ssj0001275362 035 $a(PQKBManifestationID)11757637 035 $a(PQKBTitleCode)TC0001275362 035 $a(PQKBWorkID)11236143 035 $a(PQKB)10262214 035 $a(MiAaPQ)EBC1782006 035 $a(DE-He213)978-1-4939-0265-1 035 $a(PPN)179762656 035 $a(EXLCZ)993710000000125599 100 $a20140606d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDiseases of the Sinuses $eA Comprehensive Textbook of Diagnosis and Treatment /$fedited by Christopher C. Chang, Gary A. Incaudo, M. Eric Gershwin 205 $a2nd ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (600 p.) 300 $aDescription based upon print version of record. 311 $a1-322-13269-0 311 $a1-4939-0264-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aPreface; Acknowledgments; Contents; Contributors; Part I:Anatomy and Physiology; Chapter 1: Anatomy of the Nose and Paranasal Sinuses; Anatomy of the Nose and Paranasal Sinuses; Introduction; Defining Paranasal Sinuses on the Basis of Development; Clinical Implications; An Overview of the History of Paranasal Sinus Study; Ethmoid Sinus; Development and Functional Anatomy; Clinical Implications; Maxillary Sinus; Development and Functional Anatomy; Clinical Implications; Frontal Sinus; Development and Functional Anatomy; Clinical Implications; Clinical Commentary; Sphenoid Sinus 327 $aDevelopment and Functional Anatomy Clinical Implications; Conclusions; References; Chapter 2: Physiology and Host Immune Responses of the Nose and Sinuses; Introduction; Phylogeny and Ontogeny of the Nose and Sinuses; Anatomy of the Nose and Sinuses; External Nose; Vestibule; Nasal Valve and Airflow; Nasal Septum and Turbinates; Histology of the Nose and Sinuses; Mucociliary Clearance; Vasculature; Lymphatics; Nervous System; Innate Immune Responses in the Nose; Adaptive Immunity; Pathogenesis of Chronic Rhinosinusitis; Conclusions; References 327 $aChapter 3: Immunobiology of Chronic RhinosinusitisIntroduction; The Role of Innate Immunity in Chronic Rhinosinusitis; The Epithelial Cell as an Immune Barrier in CRS; Tight Junctions; The Immune Barrier as a Mediator of T Cell Function; Other Components of Innate Immunity; S100 Protein Genes; Lymphoepithelial Kazal-Type-Related Inhibitor (LEKTI) A.K.A Serine Protease Inhibitor Kazal-Type 5 (SPINK5); Thymic Stromal Lymphopoietin (TSLP); Transforming Growth Factor (TGF); Pattern Recognition Receptors and Pathogen- and Danger-Associated Molecular Patterns; Complement and Rhinosinusitis 327 $aStaphylococcus Superantigens and Chronic Rhinosinusitis The Role of Adaptive Immunity in Chronic Rhinosinusitis; Humoral Immunity; The Role of T Cells in Chronic Rhinosinusitis; Cytokines and Chemokines in Rhinosinusitis; Cytokines; TNF-?; TGF-?; IL-6; IL-17; IL18; IL-19; IL-32; Chemokines; CCL18; CCL23; Secretoglobins in Rhinosinusitis; Conclusion; References; Chapter 4: Structural Anomalies of the Nose and Sinuses in Patients with Rhinosinusitis; Introduction; Nasal Septum; Middle Turbinate Variants; Maxillary and Frontal Sinus Drainage Pathways; Accessory Ethmoid Cells 327 $aSinus Pneumatization Neighboring Areas; Conclusion; References; Part II:Microbiology; Chapter 5: Microbiology of Acute, Subacute, and Chronic Rhinosinusitis in Children; Introduction; Acute Bacterial Sinusitis; Sinus Aspiration; Endoscopically Obtained Cultures of the Middle Meatus; Surface Cultures; The Role of Staphylococcus aureus ; The Changing Microbiology of Acute Bacterial Sinusitis; Role of Viruses; Complications; Subacute and Chronic Sinusitis; Conclusion; References; Chapter 6: Microbiology of Acute, Subacute, and Chronic Rhinosinusitis in Adults; Introduction 327 $aAcute Rhinosinusitis 330 $aDiseases of the Sinuses: A Comprehensive Textbook of Diagnosis and Treatment, 2nd Edition, offers the definitive source of information about the basic science of the sinuses and the clinical approach to sinusitis.  Since the widely praised publication of the first edition, understanding of sinus disease has changed dramatically, mainly as a result of recent developments and new discoveries in the field of immunology.  This updated and expanded edition is divided into sections addressing, separately, the pathogenesis, clinical presentation, medical and surgical management of acute and chronic rhinosinusitis.  Special entities such as autoimmune-related sinusitis, allergy and sinusitis, and aspirin-exacerbated respiratory disease are discussed in separate chapters. The role of immunodeficiency is also addressed. The management section has been fully updated to incorporate new medical modalities and surgical procedures.  Developed by a distinguished group of international experts who share their expertise and insights from years of collective experience in treating sinus diseases, the book will appeal to anyone who has an interest in sinus disease, including both physicians and allied health professionals. Internists, pediatricians, allergists, otolaryngologists and infectious disease specialists will find the book to be an invaluable, comprehensive reference. Physician assistants and nurse practitioners who work with specialists who treat sinus disease will also benefit from the book. 606 $aAllergy 606 $aPrimary care (Medicine) 606 $aInternal medicine 606 $aPediatrics 606 $aAllergology$3https://scigraph.springernature.com/ontologies/product-market-codes/H11009 606 $aPrimary Care Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H51000 606 $aInternal Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33002 606 $aPediatrics$3https://scigraph.springernature.com/ontologies/product-market-codes/H49006 615 0$aAllergy. 615 0$aPrimary care (Medicine). 615 0$aInternal medicine. 615 0$aPediatrics. 615 14$aAllergology. 615 24$aPrimary Care Medicine. 615 24$aInternal Medicine. 615 24$aPediatrics. 676 $a616.212 702 $aChang$b Christopher C$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aIncaudo$b Gary A$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGershwin$b M. Eric$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300343603321 996 $aDiseases of the Sinuses$91522979 997 $aUNINA