LEADER 04543nam 22006735 450 001 9910300342003321 005 20200705102100.0 010 $a1-4939-0817-0 024 7 $a10.1007/978-1-4939-0817-2 035 $a(CKB)3710000000202328 035 $a(EBL)1782032 035 $a(OCoLC)884960804 035 $a(SSID)ssj0001298088 035 $a(PQKBManifestationID)11761610 035 $a(PQKBTitleCode)TC0001298088 035 $a(PQKBWorkID)11240656 035 $a(PQKB)10805013 035 $a(MiAaPQ)EBC1782032 035 $a(DE-He213)978-1-4939-0817-2 035 $a(PPN)179926551 035 $a(EXLCZ)993710000000202328 100 $a20140716d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPosttranslational Protein Modifications in the Reproductive System /$fedited by Peter Sutovsky 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (259 p.) 225 1 $aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v759 300 $aDescription based upon print version of record. 311 $a1-4939-0816-2 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aSperm Proteases and Extracellular Ubiquitin-Proteasome System Involved in Fertilization of Ascidians and Sea Urchins (Hitoshi Sawada, Masako Mino and Mari Akasaka) -- Isgylation: A Conserved Pathway in Mammalian Pregnancy (Thomas R. Hansen and James K. Pru) -- Src-family Tyrosine Kinases in Oogenesis, Oocyte Maturation and Fertilization: An Evolutionary Perspective (William H. Kinsey) -- Posttranslationally Modified Tubulins and Other Cytoskeletal Proteins: Their Role in Gametogenesis, Oocyte Maturation, Fertilization and Pre-implantation Embryo Development (Heide Schatten and Qing-Yuan Sun) -- Deubiquitinating Enzymes in Oocyte Maturation, Fertilization and Preimplantation Embryo Development (Namdori R. Mtango, Keith E. Latham and Peter Sutovsky) -- Posttranslational Modifications of Zona Pellucida Proteins (Naoto Yonezawa) -- Role of aberrant protein modification, assembly and localization in cloned embryo phenotypes (Keith E. Latham) -- Role of Posttranslational Protein Modifications in Epididymal Sperm Maturation and Extracellular Quality Control (Gail A. Cornwall) -- Ubiquitin-Proteasome System in Spermatogenesis (Rohini Bose, Gurpreet Manku, Martine Culty and Simon S. Wing) -- Role of Posttranslational Modifications in C. elegans and Ascaris Spermatogenesis and Sperm Function (Long Miao and Steven W. L?Hernault). 330 $aThis book's aim is to increase the awareness of a great variety of posttranslational modifications in the male and female reproductive system. Some of the most intriguing reproductive strategies, mechanisms, and pathways involving PTM are discussed, with an added angle of evolutionary conservation and diversity. The book also chapters on sperm-egg binding, as well as on histone modification in both the embryo and sperm. Chapters are also devoted to protein ubiquitination, the regulation of sperm function during fertilization in mammals and tubulin modifications in gametes and embryos. There are no other current books on posttranslational protein modifications as they relate to reproduction, making this contribution unique in the field. It is useful for both researchers and graduate students alike. 410 0$aAdvances in Experimental Medicine and Biology,$x0065-2598 ;$v759 606 $aReproductive medicine 606 $aEndocrinology  606 $aMolecular biology 606 $aReproductive Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H56002 606 $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053 606 $aMolecular Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/B1700X 615 0$aReproductive medicine. 615 0$aEndocrinology . 615 0$aMolecular biology. 615 14$aReproductive Medicine. 615 24$aEndocrinology. 615 24$aMolecular Medicine. 676 $a572.645 702 $aSutovsky$b Peter$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910300342003321 996 $aPosttranslational Protein Modifications in the Reproductive System$91522637 997 $aUNINA