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010   $a3-662-44003-2
024 7 $a10.1007/978-3-662-44003-2
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035   $a(EBL)1967918
035   $a(SSID)ssj0001452287
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035   $a(PQKBTitleCode)TC0001452287
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035   $a(MiAaPQ)EBC1967918
035   $a(DE-He213)978-3-662-44003-2
035   $a(PPN)184497612
035   $a(EXLCZ)993710000000355366
100   $a20150204d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aRenal Tumors of Childhood $eBiology and Therapy /$fedited by Kathy Pritchard-Jones, Jeffrey S. Dome
205   $a1st ed. 2014.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014.
215   $a1 online resource (286 p.)
225 1 $aPediatric Oncology,$x2191-0812
300   $aDescription based upon print version of record.
311   $a3-662-44002-4 
320   $aIncludes bibliographical references.
327   $aEpidemiology of Renal Tumours of Childhood -- Genetic Predisposition to Wilms Tumour -- Clinical Presentation -- Pathology -- Treatment of Wilms Tumor in the Children?s Oncology Group -- Treatment of Wilms Tumor ? The SIOP approach -- Treatment of Relapsed Wilms Tumor -- Imaging -- Biological prognostic pathways -- Molecular Targeted Therapy for Pediatric Renal Tumors -- Surgical Consideration For Wilms Tumours and other Neoplastic Renal Lesions -- Radiotherapy for Wilms' Tumour and other Childhood Renal Cancers -- Late effects and QOL -- Non-Wilms Pediatrci Renal Tumors -- Wilms Tumor in Low Income Countries.
330   $aThis book provides a comprehensive overview of the biological basis of renal tumors in childhood and the clinical approaches to their treatment. Recent advances in our understanding of the molecular genetics of Wilms and other renal tumors are placed in their clinical context, including the differing treatment approaches of immediate surgery or pre-operative chemotherapy. The challenges in applying this knowledge to improve risk stratification and to incorporate biologically targeted agents into front-line therapy are discussed. In addition, the current state of thinking of the two major clinical trial groups in these diseases is presented. All of the authors are experts from Europe and North America, and the book has been written specifically as an easy reference for the practising clinician and the research scientist. It lays the basis for understanding the future direction of clinical and translational research to improve outcomes in patients with childhood renal tumors and will prove indispensable for those treating or researching into these diseases.
410  0$aPediatric Oncology,$x2191-0812
606   $aOncology
606   $aCancer$xTreatment
606   $aPediatrics
606   $aPathology
606   $aOncology
606   $aCancer Therapy
606   $aPediatrics
606   $aPathology
615  0$aOncology.
615  0$aCancer$xTreatment.
615  0$aPediatrics.
615  0$aPathology.
615 14$aOncology.
615 24$aCancer Therapy.
615 24$aPediatrics.
615 24$aPathology.
676   $a610
676   $a616.07
676   $a616994
676   $a618.92
702   $aPritchard-Jones$b Kathy$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aDome$b Jeffrey S$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910300340003321
996   $aRenal Tumors of Childhood$92544369
997   $aUNINA