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024 7 $a10.1007/978-3-642-41857-0
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035   $a(EBL)1697662
035   $a(OCoLC)881165825
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035   $a(DE-He213)978-3-642-41857-0
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035   $a(EXLCZ)992670000000548004
100   $a20140318d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aFundamentals of Evidence-Based Health Care and Translational Science /$fby Francesco Chiappelli
205   $a1st ed. 2014.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014.
215   $a1 online resource (413 p.)
300   $aDescription based upon print version of record.
311 08$aPrint version: Chiappelli, Francesco. Fundamentals of evidence-based health care and translational science 9783642418563 (OCoLC)871306841 
311 08$a3-642-41856-2 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aFundamental Implications for Clinical Practice: Translational Effectiveness in the Context of Translational Science -- Comparative Effectiveness Analysis and Evidence-Based Decisions -- The Best Available Evidence -- Sampling and Assessment of the Evidence -- Systematic Evaluation of Statistical Analysis: Data Analysis in Research Synthesis -- Optimizing Clinical Practice-Based Patient-Centered Outcomes Research: Getting and Understanding Data -- Obtaining Data -- Describing and Analyzing Data -- Translational Effectiveness Analysis -- Optimizing Clinical Outcomes by Individualizing Observations -- Evaluation in Patient-Centered Outcomes Research -- Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research.   .
330   $aComparative effectiveness research ? the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options ? is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing ?complex? systematic reviews, ?cumulative? meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.
606   $aMedicine
606   $aDrugs$xEffectiveness$xResearch$xMethodology
606   $aEvidence-based medicine
606   $aDecision making
606   $aOutcome assessment (Medical care)
606   $aComparative Effectiveness Research$3(DNLM)D057186
606   $aEvidence-Based Medicine$3(DNLM)D019317
606   $aDecision Making$3(DNLM)D003657
606   $aOutcome Assessment, Health Care$3(DNLM)D017063
606   $aMedicine/Public Health, general$3https://scigraph.springernature.com/ontologies/product-market-codes/H00007
615  0$aMedicine.
615  0$aDrugs$xEffectiveness$xResearch$xMethodology.
615  0$aEvidence-based medicine.
615  0$aDecision making.
615  0$aOutcome assessment (Medical care)
615 12$aComparative Effectiveness Research.
615 12$aEvidence-Based Medicine.
615 22$aDecision Making.
615 22$aOutcome Assessment, Health Care.
615 14$aMedicine/Public Health, general.
676   $a362.1
676   $a610
700   $aChiappelli$b Francesco$4aut$4http://id.loc.gov/vocabulary/relators/aut$0755780
906   $aBOOK
912   $a9910300335903321
996   $aFundamentals of Evidence-Based Health Care and Translational Science$91523020
997   $aUNINA