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010   $a3-642-41857-0
024 7 $a10.1007/978-3-642-41857-0
035   $a(CKB)2670000000548004
035   $a(EBL)1697662
035   $a(OCoLC)881165825
035   $a(SSID)ssj0001187202
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035   $a(PQKBTitleCode)TC0001187202
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035   $a(MiAaPQ)EBC1697662
035   $a(DE-He213)978-3-642-41857-0
035   $a(PPN)177821426
035   $a(EXLCZ)992670000000548004
100   $a20140318d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aFundamentals of Evidence-Based Health Care and Translational Science /$fby Francesco Chiappelli
205   $a1st ed. 2014.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014.
215   $a1 online resource (413 p.)
300   $aDescription based upon print version of record.
311   $a3-642-41856-2 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aFundamental Implications for Clinical Practice: Translational Effectiveness in the Context of Translational Science -- Comparative Effectiveness Analysis and Evidence-Based Decisions -- The Best Available Evidence -- Sampling and Assessment of the Evidence -- Systematic Evaluation of Statistical Analysis: Data Analysis in Research Synthesis -- Optimizing Clinical Practice-Based Patient-Centered Outcomes Research: Getting and Understanding Data -- Obtaining Data -- Describing and Analyzing Data -- Translational Effectiveness Analysis -- Optimizing Clinical Outcomes by Individualizing Observations -- Evaluation in Patient-Centered Outcomes Research -- Translational Effectiveness in Practice-Based Patient-Centered Outcomes Research.   .
330   $aComparative effectiveness research ? the conduct and synthesis of systematic research in order to compare the benefits and harms of alternative treatment options ? is of critical importance in enabling informed health care decisions to be made. This user-friendly, practical handbook examines in depth how best to perform such comparative effectiveness research. A wide range of topics and methods are discussed, including research synthesis, sampling analysis, assessment of evidence design, systematic evaluation of statistical analysis, and meta-analysis. The discussion extends well beyond the fundamentals by encompassing ?complex? systematic reviews, ?cumulative? meta-analyses, and logic-based versus utility-based decision making. Health care providers, researchers, instructors, and students will all find this to be an invaluable reference on the compelling current issues and important analytical tools in comparative effectiveness research.
606   $aMedicine
606   $aMedicine/Public Health, general$3https://scigraph.springernature.com/ontologies/product-market-codes/H00007
615  0$aMedicine.
615 14$aMedicine/Public Health, general.
676   $a362.1
676   $a610
700   $aChiappelli$b Francesco$4aut$4http://id.loc.gov/vocabulary/relators/aut$0755780
906   $aBOOK
912   $a9910300335903321
996   $aFundamentals of Evidence-Based Health Care and Translational Science$91523020
997   $aUNINA