LEADER 06082nam 22008175 450 001 9910300332203321 005 20251116154200.0 010 $a81-322-0825-0 024 7 $a10.1007/978-81-322-0825-9 035 $a(CKB)2550000001199985 035 $a(EBL)1636796 035 $a(OCoLC)868674605 035 $a(SSID)ssj0001163682 035 $a(PQKBManifestationID)11644715 035 $a(PQKBTitleCode)TC0001163682 035 $a(PQKBWorkID)11163856 035 $a(PQKB)10790252 035 $a(MiAaPQ)EBC1636796 035 $a(DE-He213)978-81-322-0825-9 035 $a(PPN)176126449 035 $a(EXLCZ)992550000001199985 100 $a20140110d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMelatonin and Melatonergic Drugs in Clinical Practice /$fedited by V. Srinivasan, Amnon Brzezinski, Sukru Oter, Samuel D. Shillcutt 205 $a1st ed. 2014. 210 1$aNew Delhi :$cSpringer India :$cImprint: Springer,$d2014. 215 $a1 online resource (405 p.) 300 $aDescription based upon print version of record. 311 08$a81-322-0824-2 320 $aIncludes bibliographical references at the end of each chapters. 327 $aMelatonin Receptors and Their Role in Human Diseases -- Melatonin?s Antioxidant Properties: Molecular Mechanisms -- Past, Present and Future of Melatonin?s Clinical Uses -- Melatonin in Human Cancer: Therapeutic  Possibilities -- Melatonin: Its Microbicidal Properties and Clinical Applications -- Melatonin and the Metabolic Syndrome -- Development of Agonists and Antagonists for Melatonin Receptors -- Multiple Facets of Melatonin in Immunity: Clinical Applications -- Melatonin and Immune Function: Clinical Significance -- Circadian Variation of Immune Mechanisms in Lung Cancer and the Role of Melatonin --  Melatonin and Melatonergic Drugs for Therapeutic Use in Breast Cancer -- Melatonin and Malaria: Therapeutic Avenues -- Melatonin's role in human reproduction: recent studies -- Melatonin Treatment and Fertility -- Melatonin and Pain: Therapeutic Applications -- Melatonin in Alzheimer?s disease: Focus on Neuroprotective Role -- Melatonin in Parkinson?s disease and its Therapeutic Potential -- Melatonin and Its Agonists in Sleep Disorders -- Agomelatine in Depressive Disorders -- Melatonin in Mood Disorders and Agomelatine?s Antidepressant Efficacy -- The Role of Agomelatine in the Treatment of Anxiety Disorders .-  Melatonin in the Etiology, Pathophysiology, and Management of Schizophrenia -- Neurobiology of Monoaminergic Neurotransmission and Antidepressants -- Melatonergic Drug - Ramelteon and Its Therapeutic Applications in Insomnia -- Melatonin?s Neuroprotective Actions on Hippocampal Neurons -- Jet Lag: Use of Melatonin and Melatonergic Drugs -- Sleep, Melatonin and Circadian Rhythmicity in Attention Deficit Hyperactivity Disorder -- Melatonergic Drugs and Their Therapeutic Use in Nasal Polyposis -- Protective Effects of Exogenous Melatonin Against Methotrexate- Induced Intestinal Injury. 330 $a The book aims to cover basic physiologic functions of melatonin, and its therapeutic applications in humans for a variety of clinically relevant disorders. This book contains chapters on the recent aspects of melatonin physiology, its receptors and their role in mitochondrial function, its immunomodulatory role and importance in seasonal dependent diseases, role in human reproduction, role in sleep, circadian rhythm and sleep disorders, role in neurologic disorders such as Parkinson?s disease, Alzheimer?s disease. Additionally, melatonin?s therapeutic use in neurobehavioral disorders in children, migraine and tension headache is also covered in this book. Melatonin?s antioxidant role in Duchenne?s muscular dystrophy and in glaucoma have also been discussed in short chapters. Two major melatonin agonists, ramelteon and agomelatine are discussed extensively on their current clinical application and ongoing research. Two chapters on agomelatonin and its role in mood disorders, particularly depressive disorders, are an important feature of this book. The chapters are written by experts from the global academia recognized for their original research and published work in the field of melatonin science. 606 $aInternal medicine 606 $aEndocrinology 606 $aPsychiatry 606 $aPsychopharmacology 606 $aNeurology 606 $aOncology 606 $aInternal Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33002 606 $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053 606 $aPsychiatry$3https://scigraph.springernature.com/ontologies/product-market-codes/H53003 606 $aPsychopharmacology$3https://scigraph.springernature.com/ontologies/product-market-codes/H53010 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 615 0$aInternal medicine. 615 0$aEndocrinology. 615 0$aPsychiatry. 615 0$aPsychopharmacology. 615 0$aNeurology. 615 0$aOncology. 615 14$aInternal Medicine. 615 24$aEndocrinology. 615 24$aPsychiatry. 615 24$aPsychopharmacology. 615 24$aNeurology. 615 24$aOncology. 676 $a612 676 $a612.492 676 $a612/.492 702 $aSrinivasan$b V.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBrzezinski$b Amnon$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aOter$b Sukru$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aShillcutt$b Samuel D.$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300332203321 996 $aMelatonin and Melatonergic Drugs in Clinical Practice$91522062 997 $aUNINA