LEADER 05450nam 22006855 450 001 9910300326403321 005 20200702113334.0 010 $a3-7091-1646-5 024 7 $a10.1007/978-3-7091-1646-3 035 $a(CKB)3710000000074766 035 $a(EBL)1593261 035 $a(SSID)ssj0001067350 035 $a(PQKBManifestationID)11705947 035 $a(PQKBTitleCode)TC0001067350 035 $a(PQKBWorkID)11080329 035 $a(PQKB)10070761 035 $a(MiAaPQ)EBC1593261 035 $a(DE-He213)978-3-7091-1646-3 035 $a(PPN)176125108 035 $a(EXLCZ)993710000000074766 100 $a20131125d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aDevelopmental Aspects of the Lymphatic Vascular System /$fedited by Friedemann Kiefer, Stefan Schulte-Merker 205 $a1st ed. 2014. 210 1$aVienna :$cSpringer Vienna :$cImprint: Springer,$d2014. 215 $a1 online resource (212 p.) 225 1 $aAdvances in Anatomy, Embryology and Cell Biology,$x0301-5556 ;$v214 300 $aDescription based upon print version of record. 311 $a3-7091-1645-7 320 $aIncludes bibliographical references and index. 327 $aIntroduction by Friedemann Kiefer -- Transcriptional control of lymphatic endothelial cell type specification by Ying Yang and Guliermo Oliver -- Mechanosensing in developing lymphatic vessels by Lara Planas-Paz and Eckard Lammert -- Plasticity of airway lymphatics in development and disease by Li-Chin Yao and Donald M. McDonald -- Regulation of lymphatic vasculature by extracellular matrix by Sophie Lutter and Taija Makkinen -- Interplay of mechanotransduction, FOXC2, connexins and calcineurin signaling in lymphatic valve formation by Amélie Sabine and Tatiana V. Petrova -- Development of secondary lymphoid organs in relation to lymphatic vasculature by Serge A. van de Pavert and Reina Mebius -- Platelets in lymph vessel development and integrity by Steve P. Watson, Kate Lowe and Brenda A. Finney -- Interactions of immune cells and lymphatic vessels by Raghu P. Kataru, Yulia G. Lee and Gou-Young Koh -- Lymphatic vessels in the development of tissue and organ rejection by Denis Hos and Claus Cursiefen.- The role of neuropilin-1 / semaphorin 3A signaling in lymphatic vessel development and maturation by Alexandra M. Ochsenbein, Sinem Karaman, Giorgia Jurisic and Michael Detmar -- A fisheye view on lymphangiogenesis by Andreas van Impel and Stefan Schulte-Merker -- Visualization of lymphatic vessel development, growth and function by Cathrin Pollmann, René Hägerling, and Friedemann Kiefer -- Clinical disorders of primary malfunctioning of the lymphatic system by Carlo Bellini and Raoul C.M. Hennekam -- Subject index. 330 $aFor decades, lymphatic vessels were considered to be of ?lesser significance? than blood vessels, and the fundamental importance of lymphatic vessels for physiological tissue homeostasis and their involvement in many pathological processes have only recently been fully appreciated. It is clear by now that all higher vertebrates possess a lymphatic vessel system, and that malfunctioning of the lymphatic vasculature has severe pathophysiological consequences. Still, many central aspects of the developmental origin, growth control and regulation of lymphatic vessels are not sufficiently understood. This volume of ?Advances in Anatomy, Embryology, and Cell Biology? focuses on the lymphatic vascular system from a developmental point of view, presenting exciting recent advances in elucidating the development and molecular control of lymphatic vessels. A collection of focused reviews, written by respected experts, describes ostensively how advanced genetic models and state-of-the-art imaging are being used to decipher the action of transcriptional programs, growth factors and matrix components in the regulation of lymphatic endothelial cell behavior. A synopsis is provided for each chapter, concisely highlighting the main points. This collection provides both an ideal introduction to lymph vessel biology for newcomers and an invaluable resource for experts. 410 0$aAdvances in Anatomy, Embryology and Cell Biology,$x0301-5556 ;$v214 606 $aHuman physiology 606 $aCell biology 606 $aImmunology 606 $aDevelopmental biology 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 606 $aCell Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L16008 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 606 $aDevelopmental Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/L18000 615 0$aHuman physiology. 615 0$aCell biology. 615 0$aImmunology. 615 0$aDevelopmental biology. 615 14$aHuman Physiology. 615 24$aCell Biology. 615 24$aImmunology. 615 24$aDevelopmental Biology. 676 $a612.42 702 $aKiefer$b Friedemann$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSchulte-Merker$b Stefan$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300326403321 996 $aDevelopmental Aspects of the Lymphatic Vascular System$91522963 997 $aUNINA