LEADER 04677nam 22005895 450 001 9910300324503321 005 20200629211215.0 010 $a3-319-55113-2 024 7 $a10.1007/978-3-319-55113-5 035 $a(CKB)4100000001381922 035 $a(DE-He213)978-3-319-55113-5 035 $a(MiAaPQ)EBC5210822 035 $a(PPN)22222987X 035 $a(EXLCZ)994100000001381922 100 $a20171228d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aIrreversible Electroporation in Clinical Practice /$fedited by Martijn R. Meijerink, Hester J. Scheffer, Govindarajan Narayanan 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (VI, 285 p. 89 illus., 72 illus. in color.) 311 $a3-319-55112-4 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aIntroduction: History of image-guided tumor ablation -- History of electroporation. Preclinical Research: Multi-scale biophysical principles in clinical irreversible electroporation -- Numerical modelling for prediction and evaluation of treatment outcome -- The effect of irreversible electroporation on blood vessels, bile ducts, urinary tract, intestines and nerves. Technique, tips and tricks: Anaesthetic management during irreversible electroporation procedure -- Complications and procedures to enhance safety -- Treatment planning, needle insertion, image-guidance, endpoint Assessment -- Thermal effects of irreversible electroporation --  Clinical practice: Irreversible electroporation of liver tumors -- Irreversible electroporation of pancreatic tumors -- Irreversible electroporation for perihilar cholangiocarcinoma (Klatskin tumors) -- Irreversible electroporation of kidney tumors -- Irreversible Electroporation of Prostate Tumors -- Irreversible electroporation of tumors within the pelvic cavity -- Irreversible Electroporation of Lung Tumors --  Future prospectives: From local to systemic treatment: leveraging antitumor immunity following irreversible electroporation -- Future perspectives of IRE. 330 $aThis book provides a comprehensive overview of the clinical use of irreversible electroporation (IRE) ? better known by its commercial name, NanoKnife ? which is one of the most exciting new needle-guided cancer treatments. The coverage includes the history of IRE, general technique, preclinical research, applications in clinical practice and early clinical results, and future perspectives. Contraindications, treatment planning, potential complications, follow-up imaging, and other practical aspects are fully discussed, with highlighting of useful tips and tricks. Through the delivery of short but highly intense electrical pulses, IRE results in tumor cell membrane permeabilization, causing cells to go into apoptosis. The minimally invasive nature of IRE, combined with the prospect of completely eradicating tumors while preserving delicate structures in the ablation zone, makes IRE the object of worldwide clinical research. This book will be of value for practitioners and trainees in interventional and diagnostic radiology, surgery, medical oncology, HPB and gastroenterology, urology, and radiation oncology. 606 $aInterventional radiology  606 $aSurgical oncology 606 $aRadiotherapy 606 $aRadiology 606 $aInterventional Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29021 606 $aSurgical Oncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H59150 606 $aRadiotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H29056 606 $aDiagnostic Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29013 615 0$aInterventional radiology . 615 0$aSurgical oncology. 615 0$aRadiotherapy. 615 0$aRadiology. 615 14$aInterventional Radiology. 615 24$aSurgical Oncology. 615 24$aRadiotherapy. 615 24$aDiagnostic Radiology. 676 $a616.0757 702 $aMeijerink$b Martijn R$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aScheffer$b Hester J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aNarayanan$b Govindarajan$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300324503321 996 $aIrreversible Electroporation in Clinical Practice$91755169 997 $aUNINA