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010   $a3-662-56179-4
024 7 $a10.1007/978-3-662-56179-9
035   $a(CKB)3840000000347736
035   $a(MiAaPQ)EBC5287480
035   $a(DE-He213)978-3-662-56179-9
035   $a(PPN)224635867
035   $a(EXLCZ)993840000000347736
100   $a20180209d2018      u|         0
101 0 $aeng
135   $aurcnu||||||||
181   $2rdacontent
182   $2rdamedia
183   $2rdacarrier
200 10$aCellular Dedifferentiation and Regenerative Medicine /$fby Xiaobing Fu, Andong Zhao, Tian Hu
205   $a1st ed. 2018.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2018.
215   $a1 online resource (291 pages)
311   $a3-662-56177-8 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aA brief history of Regeneration -- The origin of cells in Regeneration -- Cell dedifferentiation -- Cell transdifferentiation -- Cell reprogramming -- Dedifferentiation vs Transdifferentiation vs Reprogramming -- The extent of cell dedifferentiation -- Maintenance of cell differentiated identity -- Unstable differentiated state -- Epidermal cell dedifferentiation and skin regeneration -- Peripheral nerve regeneration and Schwann cell dedifferentiation -- Central nervous system and dedifferentiation -- Dedifferentiation and Heart -- Dedifferentiation and Kidney -- Dedifferentiation and other 4 systems -- The relationship between cell dedifferentiation and development of cancer and several diseases.
330   $aThis book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications. The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine. The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.
606   $aTraumatology
606   $aDermatology
606   $aRegenerative medicine
606   $aTissue engineering
606   $aTraumatic Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59125
606   $aDermatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H1900X
606   $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080
615  0$aTraumatology.
615  0$aDermatology.
615  0$aRegenerative medicine.
615  0$aTissue engineering.
615 14$aTraumatic Surgery.
615 24$aDermatology.
615 24$aRegenerative Medicine/Tissue Engineering.
676   $a571.889
700   $aFu$b Xiaobing$4aut$4http://id.loc.gov/vocabulary/relators/aut$0782384
702   $aZhao$b Andong$4aut$4http://id.loc.gov/vocabulary/relators/aut
702   $aHu$b Tian$4aut$4http://id.loc.gov/vocabulary/relators/aut
906   $aBOOK
912   $a9910300318303321
996   $aCellular Dedifferentiation and Regenerative Medicine$92065748
997   $aUNINA