LEADER 04723nam 22005655 450 001 9910300313903321 005 20200630015225.0 010 $a3-319-63483-6 024 7 $a10.1007/978-3-319-63483-8 035 $a(CKB)4100000000882246 035 $a(DE-He213)978-3-319-63483-8 035 $a(MiAaPQ)EBC5110222 035 $z(PPN)258860006 035 $a(PPN)220126089 035 $a(EXLCZ)994100000000882246 100 $a20171023d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFocus on Gynecologic Malignancies /$fedited by Nathan A. Berger, Ann H. Klopp, Karen H. Lu 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (XIII, 312 p. 17 illus., 15 illus. in color.) 225 1 $aEnergy Balance and Cancer,$x2199-2622 ;$v13 311 $a3-319-63482-8 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a1. Epidemiologic Evidence for the Obesity-Endometrial Cancer Relationship -- 2. Epidemiologic Relationship Between Obesity and Ovarian Cancer -- 3. Public Knowledge of Obesity and Gynecologic Cancer Risk -- 4. Role of Estrogen and Progesterone in Obesity Associated Gynecologic Cancers -- 5. Obesity and Endometrial Cancer Precursors -- 6. Obesity, Adipokines, and Gynecologic Cancer -- 7. Adipose Derived Stromal Cells in Gynecologic Cancers -- 8. Obesity and Endometrial Cancer: Mouse Models for Preclinical Prevention Studies -- 9. Lifestyle Interventions to Reduce the Risk of Obesity-Associated Gynecologic Malignancies: A Focus on Endometrial Cancer -- 10. Hormonal and Metabolic Strategies to Overcome Insulin Resistance and Prevent Endometrial Cancer -- 11. Management of Endometrial Cancer Precursors in Obese Women -- 12. Exercise and Lifestyle Interventions in Gynecologic Cancer Survivors -- 13. Physical Activity as a Risk Factor for Ovarian Cancer -- 14. Impact of Obesity on Surgical Approaches to Gynecologic Malignancies -- 15. Obesity, Fertility Preservation and Gynecologic Cancers -- 16. Metformin as Adjuvant Therapy in Ovarian and Endometrial Cancers. 330 $aGynecologic malignancies, especially endometrial and ovarian cancers are among the most important and most severely affected by obesity. This volume of Energy Balance and Cancer, written by the world?s leading experts in this field, is arranged to provide a transdisciplinary assessment of the pertinent issues, results of relevant research on mechanisms, and control, strategies for dealing with affected patients and improving outcomes and future research needs. The volume comprehensively covers the epidemiology linking obesity to endometrial and ovarian cancer as well as the public awareness of this critical problem. Subsequent chapters explain biologic aspects of linkages between energy balance and gynecologic malignancies. The volume further outlines strategies to disrupt the linkage between obesity and gynecologic malignancies and concludes with a series of chapters focused on management strategies for obese patients with gynecologic malignancies. This volume provides a valuable resource for all physicians, scientists and other transdisciplinary investigators and practitioners interested and involved in energy balance and cancer. It should be a particularly useful guide to optimize outcomes for all practitioners dealing with patients with gynecologic malignancies challenged by energy balance issues. Moreover, it should serve as a useful guide to students and investigators interested in conducting further research on defining and disrupting the important linkage between energy balance and gynecologic malignancies. 410 0$aEnergy Balance and Cancer,$x2199-2622 ;$v13 606 $aCancer$xResearch 606 $aGynecology 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aGynecology$3https://scigraph.springernature.com/ontologies/product-market-codes/H26006 615 0$aCancer$xResearch. 615 0$aGynecology. 615 14$aCancer Research. 615 24$aGynecology. 676 $a616.99465 702 $aBerger$b Nathan A$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKlopp$b Ann H$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aLu$b Karen H$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910300313903321 996 $aFocus on Gynecologic Malignancies$91744585 997 $aUNINA