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010   $a3-319-64994-9
024 7 $a10.1007/978-3-319-64994-8
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035   $a(DE-He213)978-3-319-64994-8
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035   $a(PPN)220128278
035   $a(EXLCZ)994100000000882255
100   $a20171023d2018      u|         0
101 0 $aeng
135   $aurnn|008mamaa
181   $ctxt$2rdacontent
182   $cc$2rdamedia
183   $acr$2rdacarrier
200 10$aOsteocardiology $eCardiac Bone Formation /$fby Nalini M. Rajamannan
205   $a1st ed. 2018.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018.
215   $a1 online resource (XIV, 99 p. 22 illus. in color.) 
311   $a3-319-64993-0 
320   $aIncludes bibliographical references at the end of each chapters.
327   $aOsteocardiology: Risk Factors -- Osteocardiology: Coronary Artery Calcification -- Osteocardiology: Calcific Aortic Valve Disease -- Osteocardiology: Calcific Aortic Disease -- Osteocardiology: Endochondral Bone Formation -- Osteocardiology: The Atherosclerotic Bone Paradox -- Osteocardiology: Cellular Origins of Cardiac Calcification -- Osteocardiology: LDL-Density-Gene Theory -- Osteocardiology: The LDL-Density-Mechanostat Theory -- Osteocardiology: The Go/No Go Theory For Clinical Trials.
330   $aThis book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critical elements of atherosclerosis, including foam cell formation, vascular smooth muscle cell proliferation and extracellular matrix synthesis, which over time forms bone in the heart. Osteocardiology: Cardiac Bone Formation is a practical overview of bone formation in the heart and is destined to become the cornerstone for education of medical students, residents, fellows, graduate students, physician scientists and scientists, for future research and ongoing development in medical therapies to slow or halt the progression of bone formation in the heart.
606   $aCardiology
606   $aHuman physiology
606   $aCardiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33037
606   $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004
615  0$aCardiology.
615  0$aHuman physiology.
615 14$aCardiology.
615 24$aHuman Physiology.
676   $a616.12
700   $aRajamannan$b Nalini M$4aut$4http://id.loc.gov/vocabulary/relators/aut$0787350
906   $aBOOK
912   $a9910300313003321
996   $aOsteocardiology$91754118
997   $aUNINA