LEADER 03935nam 22005295 450 001 9910300305003321 005 20200705060836.0 010 $a981-10-1412-4 024 7 $a10.1007/978-981-10-1412-3 035 $a(CKB)4100000002892583 035 $a(MiAaPQ)EBC5428748 035 $a(DE-He213)978-981-10-1412-3 035 $a(PPN)225548933 035 $a(EXLCZ)994100000002892583 100 $a20180301d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aCell Therapy for Perinatal Brain Injury$b[electronic resource] /$fedited by Haruo Shintaku, Akira Oka, Makoto Nabetani 205 $a1st ed. 2018. 210 1$aSingapore :$cSpringer Singapore :$cImprint: Springer,$d2018. 215 $a1 online resource (xii, 150 pages) $cillustrations 311 $a981-10-1411-6 327 $a1. Clinical trial of autologous cord blood cell therapy for neonatal hypoxic?ischemic encephalopathy (HIE) -- 2. New strategy of clinical studies for premature babies with ischemic brain damage -- 3. Pathophysiology and pathology of neonatal hypoxic-ischemic encephalopathy -- 4. Neural stem/progenitor cells for perinatal brain injury -- 5. Hematopoietic stem cells for perinatal brain injury -- 6. Umbilical cord-derived mesenchymal stromal cells for perinatal brain injury -- 7. Other tissues-derived mesenchymal stem cells for perinatal brain injury -- 8. CD34+ cell in cord blood and neonates -- 9. The History of Hypothermia therapy for perinatal ischemic brain injury -- 10. Clinical Procedure of Cell Therapy (Cord blood collection) -- 11. Clinical Procedure of Cell Therapy (Separation and infusion) -- 12. Cell therapy for adult infarction -- 13. Clinical trials on cell therapy for perinatal brain injury: Challenges and opportunities -- 14. A new prospective cell therapy for neonatal brain injury. 330 $aThis book provides a wealth of insights, advances and new perspectives on cell therapy for different types of neonatal ischemic disease, such as Hypoxic-Ischemic Encephalopathy (HIE), Periventricular Leukomalacia (PVL) and neonatal infarction. These diseases pose serious challenges for neonatologists and neurologists, because the severe sequelae lead to decreasing QOL for patients and their families. Accordingly, new treatments for neonatal ischemic diseases are needed all over the world. The book develops new effective therapies combined with hypothermia therapy, an established treatment for HIE. After reviewing past approaches, it presents cutting-edge topics in cell therapy, one of the most promising candidates for treating neonatal ischemic disease. Cell Therapy for Neonatal Ischemic Disease will offer readers a better understanding of the current state of the art in this field from bench to bedside, and inspire researchers and physicians to further explore this evolving therapy. 606 $aPediatrics 606 $aNeurology  606 $aObstetrics 606 $aPediatrics$3https://scigraph.springernature.com/ontologies/product-market-codes/H49006 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 606 $aObstetrics/Perinatology/Midwifery$3https://scigraph.springernature.com/ontologies/product-market-codes/H26014 615 0$aPediatrics. 615 0$aNeurology . 615 0$aObstetrics. 615 14$aPediatrics. 615 24$aNeurology. 615 24$aObstetrics/Perinatology/Midwifery. 676 $a617.481044 702 $aShintaku$b Haruo$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aOka$b Akira$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aNabetani$b Makoto$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300305003321 996 $aCell Therapy for Perinatal Brain Injury$91743009 997 $aUNINA