LEADER 00711nam0-22002771i-450- 001 990001609000403321 005 20050201114700.0 035 $a000160900 035 $aFED01000160900 035 $a(Aleph)000160900FED01 035 $a000160900 100 $a20030910d1907----km-y0itay50------ba 101 0 $aita 200 1 $aDelle ipoteche$fPasquale Melucci 210 $aNapoli$cPironti$d1907 215 $a324 p.$d25 cm 610 0 $aIpoteche 676 $a346.043 6 700 1$aMelucci,$bPasquale$06266 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990001609000403321 952 $a60 347.27 B 1$b19832$fFAGBC 959 $aFAGBC 996 $aDelle ipoteche$9369010 997 $aUNINA LEADER 03663nam 22005295 450 001 9910300291403321 005 20251116195609.0 010 $a3-319-73506-3 024 7 $a10.1007/978-3-319-73506-1 035 $a(CKB)4100000003359283 035 $a(MiAaPQ)EBC5356100 035 $a(DE-He213)978-3-319-73506-1 035 $a(PPN)226698610 035 $a(EXLCZ)994100000003359283 100 $a20180413d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aHandbook of Sepsis /$fedited by W. Joost Wiersinga, Christopher W. Seymour 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (viii, 267 pages) $cillustrations 311 08$a3-319-73505-5 320 $aIncludes bibliographical references. 327 $aPART 1. SEPSIS: AN OVERVIEW:.-1. What is sepsis? -- 2. The epidemiology of sepsis -- PART 2. THE PATHOGENESIS OF SEPSIS: -- 3.The pathogenesis -- 4.The coagulation system in sepsis.-5.The endocrine system in sepsis -- 6.Biomarkers for sepsis -- PART 3.SEPSIS MANAGEMENT: -- 7.International clinical practice guidelines -- 8. Fluids -- 9.Vasopressors -- 10. Multiorgan failure -- 11.Importance of the pathogen -- 12.Antimicrobial therapy -- 13.Adjunctive immunotherapy -- PART IV. SEPSIS IN THE COMING DECADE: -- 14.Novel trial design in sepsis -- 15. Sepsis in low- and middle income countries -- 16 Sepsis: the road ahead. 330 $aThis practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is international in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students. 606 $aInfectious diseases 606 $aCritical care medicine 606 $aGeneral practice (Medicine) 606 $aInfectious Diseases$3https://scigraph.springernature.com/ontologies/product-market-codes/H33096 606 $aIntensive / Critical Care Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H3100X 606 $aGeneral Practice / Family Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H24003 615 0$aInfectious diseases. 615 0$aCritical care medicine. 615 0$aGeneral practice (Medicine). 615 14$aInfectious Diseases. 615 24$aIntensive / Critical Care Medicine. 615 24$aGeneral Practice / Family Medicine. 676 $a616.944 702 $aWiersinga$b W. Joost$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSeymour$b Christopher W$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300291403321 996 $aHandbook of Sepsis$91753197 997 $aUNINA