LEADER 02957nam 22004575 450 001 9910300282103321 005 20200704204834.0 010 $a3-319-89866-3 024 7 $a10.1007/978-3-319-89866-7 035 $a(CKB)4100000004836399 035 $a(DE-He213)978-3-319-89866-7 035 $a(MiAaPQ)EBC5434942 035 $a(PPN)229497837 035 $a(EXLCZ)994100000004836399 100 $a20180621d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aChimerism $eA Clinical Guide /$fedited by Nicole L. Draper 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (XI, 200 p. 20 illus., 15 illus. in color.) 311 $a3-319-89865-5 327 $aFertilization and Early Embryonic Errors -- Pregnancy and Multiple Gestations -- Transplantation and Transfusion -- Relationship Testing and Forensics -- Prenatal Genetic Testing and Screening -- Blood Typing Discrepancies -- Hematopoietic Stem Cell Donor Selection and Graft-Versus-Host Disease -- Passenger Lymphocyte Syndrome -- Chimerism: A Clinical Guide to Tolerance Induction -- Autoimmune Disease -- Cancer. 330 $aThis text provides a comprehensive, up-to-date review of chimerism. The first part of the volume presents the causes of chimerism, specifically focusing on fertilization and early embryonic errors, pregnancy and multiple gestations, and transplantation and transfusion. The second part of the volume outlines clinical identification and consequences of chimerism. Chapters in this section focus on the effects of chimerism on testing in relationship determination and forensics, prenatal genetic testing and screening, and blood and HLA typing. This part also reviews new data concerning matching donors and recipients for transplantation, while outlining the risks of transplantation, such as graft-vs-host disease and passenger lymphocyte syndrome. Additionally, evidence on the role of chimerism in autoimmune disease and cancer is presented. Written by experts in the field, Chimerism: A Clinical Guide is a valuable resource for clinicians and researchers that will help guide patient management and stimulate investigative efforts. 606 $aHematology 606 $aBlood transfusion 606 $aHematology$3https://scigraph.springernature.com/ontologies/product-market-codes/H3307X 606 $aBlood Transfusion Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33029 615 0$aHematology. 615 0$aBlood transfusion. 615 14$aHematology. 615 24$aBlood Transfusion Medicine. 676 $a616.15 702 $aDraper$b Nicole L$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300282103321 996 $aChimerism$91743095 997 $aUNINA