LEADER 02920nam 22005055 450 001 9910300271603321 005 20200704182547.0 010 $a3-319-72938-1 024 7 $a10.1007/978-3-319-72938-1 035 $a(CKB)4100000002892223 035 $a(MiAaPQ)EBC5341338 035 $a(DE-He213)978-3-319-72938-1 035 $a(PPN)225553295 035 $a(EXLCZ)994100000002892223 100 $a20180315d2018 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aNeurodegenerative Diseases $eClinical Aspects, Molecular Genetics and Biomarkers /$fedited by Daniela Galimberti, Elio Scarpini 205 $a2nd ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (407 pages) $cillustrations 311 $a3-319-72937-3 330 $aThis book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer?s disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson?s disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields. 606 $aNeurology  606 $aNeurosciences 606 $aHuman genetics 606 $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008 615 0$aNeurology . 615 0$aNeurosciences. 615 0$aHuman genetics. 615 14$aNeurology. 615 24$aNeurosciences. 615 24$aHuman Genetics. 676 $a616.8047 702 $aGalimberti$b Daniela$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aScarpini$b Elio$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300271603321 996 $aNeurodegenerative Diseases$91522227 997 $aUNINA