LEADER 05112nam 22007215 450 001 9910300259003321 005 20200702122106.0 010 $a3-319-23497-8 024 7 $a10.1007/978-3-319-23497-7 035 $a(CKB)3710000000521706 035 $a(EBL)4179381 035 $a(SSID)ssj0001585292 035 $a(PQKBManifestationID)16263866 035 $a(PQKBTitleCode)TC0001585292 035 $a(PQKBWorkID)14864754 035 $a(PQKB)10486947 035 $a(DE-He213)978-3-319-23497-7 035 $a(MiAaPQ)EBC4179381 035 $a(PPN)190520957 035 $a(EXLCZ)993710000000521706 100 $a20151126d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMathematical Models in Biology $eBringing Mathematics to Life /$fedited by Valeria Zazzu, Maria Brigida Ferraro, Mario R. Guarracino 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (207 p.) 300 $a"Bringing Maths to life" workshop, held in Naples, Italy, October 27-29, 2014." 311 $a3-319-23496-X 320 $aIncludes bibliographical references at the end of each chapters. 327 $aImage segmentation, processing and analysis in microscopy and life science -- Image analysis and classification for high-throughput screening of embryonic stem cells -- Exploiting ?mental? images in artificial neural network computation -- Applying design of experiment methodology to PEI toxicity assay on neural progenitor cells -- A design of experiment approach to optimize an image analysis protocol for drug screening -- Computational modeling of miRNA biogenesis -- Tunicate neurogenesis: the case of the SoxB2 missing CNE -- MECP2: a multifunctional protein supporting brain complexity -- DNA barcode classification using general regression neural network with different distance models -- First application of a distance-based outlier approach to detect highly differentiated genomic regions across human populations -- Predicting the metagenomic content using multiple CART trees -- A statistical approach to infer 3D chromatin structure -- Basic exploratory proteins analysis with statistical methods applied on structural features -- Modeling of Protein Surface using Parallel Heterogeneous Architectures. 330 $aThis book presents an exciting collection of contributions based on the workshop ?Bringing Maths to Life? held October 27-29, 2014 in Naples, Italy.  The state-of-the art research in biology and the statistical and analytical challenges facing huge masses of data collection are treated in this Work. Specific topics explored in depth surround the sessions and special invited sessions of the workshop and include genetic variability via differential expression, molecular dynamics and modeling, complex biological systems viewed from quantitative models, and microscopy images processing, to name several. In depth discussions of the mathematical analysis required to extract insights from complex bodies of biological datasets, to aid development in the field novel algorithms, methods and software tools for genetic variability, molecular dynamics, and complex biological systems are presented in this book. Researchers and graduate students in biology, life science, and mathematics/statistics will find the content useful as it addresses existing challenges in identifying the gaps between mathematical modeling and biological research. The shared solutions will aid and promote further collaboration between life sciences and mathematics. 606 $aBiomathematics 606 $aLife sciences 606 $aMatrix theory 606 $aAlgebra 606 $aMathematical analysis 606 $aAnalysis (Mathematics) 606 $aMathematical and Computational Biology$3https://scigraph.springernature.com/ontologies/product-market-codes/M31000 606 $aLife Sciences, general$3https://scigraph.springernature.com/ontologies/product-market-codes/L00004 606 $aLinear and Multilinear Algebras, Matrix Theory$3https://scigraph.springernature.com/ontologies/product-market-codes/M11094 606 $aAnalysis$3https://scigraph.springernature.com/ontologies/product-market-codes/M12007 615 0$aBiomathematics. 615 0$aLife sciences. 615 0$aMatrix theory. 615 0$aAlgebra. 615 0$aMathematical analysis. 615 0$aAnalysis (Mathematics). 615 14$aMathematical and Computational Biology. 615 24$aLife Sciences, general. 615 24$aLinear and Multilinear Algebras, Matrix Theory. 615 24$aAnalysis. 676 $a510 702 $aZazzu$b Valeria$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aFerraro$b Maria Brigida$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGuarracino$b Mario R$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300259003321 996 $aMathematical models in biology$91522785 997 $aUNINA