LEADER 04325nam 22007095 450 001 9910300238303321 005 20200702040549.0 010 $a3-319-17235-2 024 7 $a10.1007/978-3-319-17235-4 035 $a(CKB)3710000000415667 035 $a(EBL)2094703 035 $a(SSID)ssj0001501647 035 $a(PQKBManifestationID)11918713 035 $a(PQKBTitleCode)TC0001501647 035 $a(PQKBWorkID)11446002 035 $a(PQKB)10234920 035 $a(DE-He213)978-3-319-17235-4 035 $a(MiAaPQ)EBC2094703 035 $a(PPN)186026455 035 $a(EXLCZ)993710000000415667 100 $a20150518d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aPancreatic Neuroendocrine Neoplasms $ePractical Approach to Diagnosis, Classification, and Therapy /$fedited by Stefano La Rosa, Fausto Sessa 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (195 p.) 300 $aDescription based upon print version of record. 311 $a3-319-17234-4 320 $aIncludes bibliographical references at the end of each chapters. 327 $aHistorical background and epidemiology -- Radiological diagnosis -- Nuclear medicine diagnosis -- Endocrinological approach to diagnosis -- Cytological diagnosis -- Classification -- Immunohistochemical approach to diagnosis -- Insulinoma -- Glucagonoma -- Somatostatinoma -- VIPoma -- Gastrinoma -- ACTH-producing tumor -- Serotonin-producing tumor -- GRF-, GH-, Ghrelin- and PTH-producing tumor -- Nonfunctioning pancreatic neuroendocrine neoplasms including PP-, calcitonin- and neurotensin-producing tumors -- Poorly differentiated neuroendocrine carcinoma of the pancreas -- Mixed adenoneuroendocrine carcinoma of the pancreas -- Hyperplastic and dysplastic pancreatic neuroendocrine lesions -- Molecular pathology -- Surgical therapy -- Pharmacological therapy. 330 $aThis book provides a broad overview of pancreatic neuroendocrine neoplasms, focusing on the most important developments in the technologies used to diagnose, classify, and treat them. After a historical and epidemiological overview, the opening chapters examine the various diagnostic approaches (radiology, nuclear medicine, endocrinology, cytology, and immunohistochemistry) and discuss the WHO classification. The functioning and nonfunctioning tumor types are then fully discussed, covering epidemiology, diagnosis, morphology, and prognosis of each entity. Careful consideration is given to the molecular features that have contributed in understanding the pathogenesis of such neoplasms and may have potential implications for the diagnostic and therapeutic pathways. The final chapters consider the surgical and medical approaches to therapy, providing a practical and analytical overview of the available options. The book is written by a multidisciplinary team of worldwide-recognized experts and is addressed to radiologists, nuclear medicine physicians, endocrinologists, pathologists, surgeons, and oncologists. 606 $aOncology   606 $aPathology 606 $aEndocrinology  606 $aRadiology 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aEndocrinology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33053 606 $aImaging / Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29005 615 0$aOncology  . 615 0$aPathology. 615 0$aEndocrinology . 615 0$aRadiology. 615 14$aOncology. 615 24$aPathology. 615 24$aEndocrinology. 615 24$aImaging / Radiology. 676 $a610 676 $a616.07 676 $a616.0757 676 $a616.4 676 $a616994 702 $aLa Rosa$b Stefano$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aSessa$b Fausto$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300238303321 996 $aPancreatic Neuroendocrine Neoplasms$92529257 997 $aUNINA