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005 20200705231331.0
010   $a3-662-45698-2
024 7 $a10.1007/978-3-662-45698-9
035   $a(CKB)3710000000372115
035   $a(EBL)1998373
035   $a(SSID)ssj0001465385
035   $a(PQKBManifestationID)11808989
035   $a(PQKBTitleCode)TC0001465385
035   $a(PQKBWorkID)11471681
035   $a(PQKB)10032607
035   $a(DE-He213)978-3-662-45698-9
035   $a(MiAaPQ)EBC1998373
035   $a(PPN)184888565
035   $a(EXLCZ)993710000000372115
100   $a20150305d2015      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aBlistering Diseases $eClinical Features, Pathogenesis, Treatment /$fedited by Dédée F. Murrell
205   $a1st ed. 2015.
210  1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2015.
215   $a1 online resource (724 p.)
300   $aDescription based upon print version of record.
311   $a3-662-45697-4 
327   $aPathogenesis -- Diagnostic Tests -- Epidemiology -- Clinical Presentation of Epidermal Disorders -- Clinical Presentation of Lamina Lucida Disorders -- Clinical Presentation of Lamina Densa Disorders -- Clinical Presentation of Disease in Mixed Locations -- General Management of Auto-Immune Blistering Disease -- Management of Individual Diseases Management of Epidermolysis Bullosa.
330   $aThis book is a comprehensive compendium of current knowledge on inherited and autoimmune blistering diseases that relates advances in our understanding of the pathogenetic mechanisms to management of the individual diseases. The aim is to provide a detailed reference for dermatologists who care for patients with these conditions and a useful ?one-stop information shop? for specialists outside of dermatology. The book opens by describing the structure and biology of the epidermis and basement membrane zone and discussing the genes and proteins that are targets for mutations and autoantibodies. The role of the various diagnostic tests is explained, and clinical manifestations of the specific diseases are presented with the aid of many high-quality illustrations. The forms of treatment appropriate in specific conditions are then described in depth, with coverage of dressings, drugs, surgical procedures, gene therapy, and other novel approaches. Helpful algorithms are included both for testing and monitoring and for treatment.
606   $aDermatology
606   $aPathology
606   $aPediatrics
606   $aInternal medicine
606   $aDermatology$3https://scigraph.springernature.com/ontologies/product-market-codes/H1900X
606   $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X
606   $aPediatrics$3https://scigraph.springernature.com/ontologies/product-market-codes/H49006
606   $aInternal Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H33002
615  0$aDermatology.
615  0$aPathology.
615  0$aPediatrics.
615  0$aInternal medicine.
615 14$aDermatology.
615 24$aPathology.
615 24$aPediatrics.
615 24$aInternal Medicine.
676   $a616.5
702   $aMurrell$b Dédée F$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910300236403321
996   $aBlistering Diseases$91760474
997   $aUNINA