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010   $a3-319-16949-1
024 7 $a10.1007/978-3-319-16949-1
035   $a(CKB)3710000000412173
035   $a(EBL)2094671
035   $a(SSID)ssj0001501580
035   $a(PQKBManifestationID)11901922
035   $a(PQKBTitleCode)TC0001501580
035   $a(PQKBWorkID)11446981
035   $a(PQKB)11047396
035   $a(DE-He213)978-3-319-16949-1
035   $a(MiAaPQ)EBC2094671
035   $a(PPN)186026358
035   $a(EXLCZ)993710000000412173
100   $a20150506d2015      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aLocal Treatment of Inflammatory Joint Diseases $eBenefits and Risks /$fedited by Willm Uwe Kampen, Manfred Fischer
205   $a1st ed. 2015.
210  1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015.
215   $a1 online resource (147 p.)
300   $aDescription based upon print version of record.
311   $a3-319-16948-3 
320   $aIncludes bibliographical references.
327   $aPreface -- Histopathology of synovitis -- Non-radioactive treatment of synovitis (risk-benefit) -- Introduction to radiosynoviorthesis (RSO) -- Dosimetry and radiation burden -- Local complications and possible treatment strategies -- Risk of malignoma induction -- Baker´s cysts ? a relevant contraindication?.- Analysis of periodic update reports -- Summary.
330   $aThis book presents a systematic survey of different local treatments in inflammatory joint diseases and their potential side effects and complications. Both surgical therapies and pharmaceutical strategies involving local or systemic application of anti-inflammatory and immunomodulating drugs are addressed. Special emphasis is placed on nuclear medicine therapy by intra-articular instillation of beta radiation emitters, known as radiosynoviorthesis or radiation synovectomy. Possible complications, in particular radionecrosis, infection, and thromboembolism, are described and available treatment strategies are examined in detail. In addition, radiation safety considerations are critically reviewed and relevant clinical questions are discussed.  While radiosynoviorthesis is an effective and safe treatment if a proper indication is secured and if the application is performed by an experienced nuclear medicine physician, local complications can never be excluded with certainty. This book will support physicians who are engaged in the care and treatment of patients with inflammatory joint disease, approximately 30,000 of whom undergo radiosynoviorthesis in Europe each year.  .
606   $aNuclear medicine
606   $aRadiotherapy
606   $aNuclear Medicine$3https://scigraph.springernature.com/ontologies/product-market-codes/H29048
606   $aRadiotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H29056
615  0$aNuclear medicine.
615  0$aRadiotherapy.
615 14$aNuclear Medicine.
615 24$aRadiotherapy.
676   $a610
676   $a615842
676   $a616.07548
702   $aKampen$b Willm Uwe$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aFischer$b Manfred$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910300212103321
996   $aLocal Treatment of Inflammatory Joint Diseases$92533814
997   $aUNINA