LEADER 06172nam 22007215 450 001 9910300194203321 005 20200705134218.0 010 $a0-85729-597-7 024 7 $a10.1007/978-0-85729-597-2 035 $a(CKB)3710000000341759 035 $a(EBL)1964682 035 $a(SSID)ssj0001424613 035 $a(PQKBManifestationID)11832264 035 $a(PQKBTitleCode)TC0001424613 035 $a(PQKBWorkID)11367521 035 $a(PQKB)10182774 035 $a(DE-He213)978-0-85729-597-2 035 $a(MiAaPQ)EBC1964682 035 $a(PPN)183515641 035 $a(EXLCZ)993710000000341759 100 $a20150124d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aStereotactic Body Radiotherapy $eA Practical Guide /$fedited by Andrew Gaya, Anand Mahadevan 205 $a1st ed. 2015. 210 1$aLondon :$cSpringer London :$cImprint: Springer,$d2015. 215 $a1 online resource (336 p.) 300 $aDescription based upon print version of record. 311 $a0-85729-596-9 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aContents; Contributors; Chapter 1: Introduction to Stereotactic Body Radiotherapy; 1.1 History of SBRT; 1.2 Fractionation and Radiobiology; 1.3 Overview of SBRT Systems; 1.4 Respiratory Motion; 1.5 Summary of Major SBRT Indications; 1.5.1 Primary Non-Small Cell Lung Cancer (NSCLC); 1.5.2 Lung Oligometastases; 1.5.3 Liver Metastases; 1.5.4 Primary Liver Tumours; 1.5.5 Pancreas; 1.5.6 Kidney; 1.5.7 Prostate; 1.5.8 Vertebral Metastases; 1.5.9 Primary Spinal Tumors; 1.6 Conclusion; References; Chapter 2: History and the Technological Evolution of Stereotactic Body Radiotherapy; 2.1 Introduction 327 $a2.2 Clinical Evolution of SBRT2.3 Devices, Delivery System and Localization: Early Techniques and Technology; 2.4 Radiobiological Rationale and Its Impact on SBRT Techniques; 2.5 Evolution to Treat Other Sites; 2.6 Conclusion; References; Chapter 3: Stereotactic Body Radiation Therapy Systems; 3.1 Introduction; 3.2 System Components and Requirements; 3.2.1 Patient Immobilization; 3.2.2 Image-Guided Localization and Tracking; 3.2.3 Simulation and Other Imaging Modalities; 3.2.4 Beam Characteristics; 3.2.5 Planning; 3.2.6 Quality Assurance in SBRT; 3.3 Commercially Available Systems; References 327 $aChapter 4: Physics of Stereotactic Body Radiotherapy-Commissioning, Quality Assurance, and Treatment Planning4.1 Introduction; 4.2 SBRT System Commissioning; 4.2.1 Beam Data; 4.2.2 Data Acquisition; 4.2.3 TPS Commissioning; 4.3 Quality Assurance; 4.3.1 Imaging System Quality Assurance; 4.3.2 Dosimetric Quality Assurance; 4.3.2.1 Validation Measurement Vs. Treatment Planning Output; 4.3.2.2 Routine Quality Assurance Program; Beam Stability Test; End-to-End Test: Including Motion Tracking/Gating End-to-End Test; 4.3.3 Patient Specific QA; 4.4 Treatment Planning; 4.4.1 Introduction 327 $a4.4.2 Simulation, Motion Management and Target Delineation4.4.3 Dose Heterogeneity and Prescription Normalization; 4.4.4 Practical Considerations; References; Further Reading: Quality Assurance; Further Reading List: Treatment Planning; Chapter 5: Radiobiology of High Dose Fractions; 5.1 Introduction; 5.2 The Basic LQ Model; 5.3 Example of Simple LQ Modelling; 5.3.1 Allowance for "Straightening-Out" of the Dose-Response Curve; 5.3.2 Normal Tissue "Hot-Spots"; 5.4 Other Radiobiological Factors; 5.4.1 Tumour Repopulation; 5.4.2 Problems with Incomplete-Repair Following Large Dose Fractions 327 $a5.4.3 Effect of Extended Fraction Times5.4.4 Effect of Cell Cycle Re-Assortment and Re-Oxygenation; 5.4.5 Normal Tissue Volume Effects; 5.4.6 Tumour Volume Effects (and Volume Changes with Time); 5.5 Other Relevant Clinical Factors; 5.5.1 Co-Morbidity from Other Sources; 5.5.2 High-Let and RBE Issues for Hypofractionation; 5.6 Conclusions and Future Implications; References; Chapter 6: Planning and Dosimetry for Stereotactic Body Radiotherapy; 6.1 Introduction; 6.2 Basic Principles of SBRT Planning: Homogeneous Vs. Heterogeneous Planning; 6.3 General Concepts for SRS/SBRT Planning 327 $a6.4 Treatment Delivery Time 330 $aThis practical guide covers the basic  aspects of stereotactic radiotherapy systems and treatment. As an emerging field, stereotactic body radiotherapy (SBRT) offers image-guided radiation that is directed at extremely well-defined tumor targets within the body, delivering very high doses of radiation.  Indications for SBRT have expanded extensively in recent years from intracranial treatment to extracranial, leading to the development of a thriving subspecialty within radiation oncology.   The expertise on these methods is concentrated across a few centres, mainly in the USA. However, as the technique is increasingly being adopted worldwide, specialists require further training in using it. Stereotactic Body Radiotherapy ? A Practical Guide provides a valuable aid for this purpose and is of particular interest to clinical oncologists and their trainees. 606 $aRadiotherapy 606 $aOncology   606 $aRadiology 606 $aRadiotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H29056 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aImaging / Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29005 615 0$aRadiotherapy. 615 0$aOncology  . 615 0$aRadiology. 615 14$aRadiotherapy. 615 24$aOncology. 615 24$aImaging / Radiology. 676 $a610 676 $a615.82 676 $a615842 676 $a616994 676 $a615.842 702 $aGaya$b Andrew$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMahadevan$b Anand$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300194203321 996 $aStereotactic Body Radiotherapy$91770936 997 $aUNINA