LEADER 04513nam 22007935 450 001 9910300189503321 005 20200706053104.0 010 $a2-8178-0484-8 024 7 $a10.1007/978-2-8178-0484-2 035 $a(CKB)3710000000343727 035 $a(EBL)1969292 035 $a(SSID)ssj0001424625 035 $a(PQKBManifestationID)11832266 035 $a(PQKBTitleCode)TC0001424625 035 $a(PQKBWorkID)11368743 035 $a(PQKB)10663142 035 $a(DE-He213)978-2-8178-0484-2 035 $a(MiAaPQ)EBC1969292 035 $a(PPN)18351582X 035 $a(EXLCZ)993710000000343727 100 $a20150129d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aTechnical Aspects of Focal Therapy in Localized Prostate Cancer /$fedited by Eric Barret, Matthieu Durand 205 $a1st ed. 2015. 210 1$aParis :$cSpringer Paris :$cImprint: Springer,$d2015. 215 $a1 online resource (252 p.) 300 $aDescription based upon print version of record. 311 $a2-8178-0483-X 320 $aIncludes bibliographical references at the end of each chapters. 327 $aRational for Focal Therapy -- Concept of Index lesion -- Definition and Principles of Focal Therapy -- Eligibility for Focal Therapy: Patient Selection -- Imagingfor Focal Therapy -- Biopsies strategy -- Focal Cryotherapy -- Focal HIFU -- Focal Brachytherapy -- Focal PhotoDynamic Therapy -- Focal Laser Thermal Therapy -- Cyberknife Focal Therapy -- New Energies -- Follow-up after Focal Therapy -- Failure or Recurrence Management -- Focal Therapy Limitations -- Perspective -- Conclusion. 330 $aFocal therapy is a promising option for selected patients who have localized low or intermediate-risk prostate cancer, providing a compelling alternative between active surveillance and radical therapies by targeting the index lesion and preserving as much tissue as possible. Numerous cohort studies have already investigated multiple focal techniques, such as cryotherapy, high-intensity focused ultrasound, brachytherapy, photodynamic therapy, laser therapy, irreversible electroporation and cyberknife methods, all of which have demonstrated positive oncological outcomes with 70 to 90 % negative follow-up biopsy. These various ablative techniques have produced only minor side-effects concerning urinary function, a low rate of erectile dysfunction, and have demonstrated a limited rectal toxicity. As a result, the primary end-point has now shifted and a new strategy needs to be established for patient follow-up and for defining treatment failure. Written by international experts in the field, this book is mainly focused on new techniques, all of which are amply illustrated. Technical Aspects of Focal Therapy in Localized Prostate Cancer will be of great practical value to all urologists and oncologists. 606 $aOncology 606 $aUrology 606 $aRadiology 606 $aInterventional radiology 606 $aCancer$xSurgery 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aUrology$3https://scigraph.springernature.com/ontologies/product-market-codes/H62002 606 $aImaging / Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29005 606 $aUltrasound$3https://scigraph.springernature.com/ontologies/product-market-codes/H29064 606 $aInterventional Radiology$3https://scigraph.springernature.com/ontologies/product-market-codes/H29021 606 $aSurgical Oncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H59150 615 0$aOncology. 615 0$aUrology. 615 0$aRadiology. 615 0$aInterventional radiology. 615 0$aCancer$xSurgery. 615 14$aOncology. 615 24$aUrology. 615 24$aImaging / Radiology. 615 24$aUltrasound. 615 24$aInterventional Radiology. 615 24$aSurgical Oncology. 676 $a610 676 $a616.07543 676 $a616.0757 676 $a616.6 676 $a616994 676 $a616.9946306 702 $aBarret$b Eric$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDurand$b Matthieu$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300189503321 996 $aTechnical Aspects of Focal Therapy in Localized Prostate Cancer$91813327 997 $aUNINA