LEADER 01039nkm2-2200325---450- 001 990009986490403321 005 20150723112814.0 035 $a000998649 035 $aFED01000998649 035 $a(Aleph)000998649FED01 035 $a000998649 100 $a20150723f19601970km-y0itay50------ba 101 0 $ager 102 $aDE 116 $ahe-c-------------- 200 1 $aLandschaft in Ost-Java$bRisorsa grafica 210 $aBraunschweig$cGeorg Westermann Verlag$d[196.] 215 $a1 diapositiva$ccol.$d36 x 24 mm su supporto di cartone 50 x 50 mm 300 $aTit. aggiunto in ital. rilevato dagli archivi dell'ex Ist. di Geografia 463 0$1001000998613 540 1 $aPaesaggio, Giava orientale 610 0 $aIndonesia$aGiava$aPaesaggio$aImmagini 710 02$aGeorg Westermann Verlag$0129269 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aGR 912 $a990009986490403321 952 $aScat. West. I-02(007)$bIst. s.i.$fILFGE 959 $aILFGE 996 $aLandschaft in Ost-Java$91499225 997 $aUNINA LEADER 03944nam 22006015 450 001 9910300186603321 005 20230823102946.0 010 $a3-662-43733-3 024 7 $a10.1007/978-3-662-43733-9 035 $a(CKB)3710000000306291 035 $a(EBL)1966018 035 $a(SSID)ssj0001386612 035 $a(PQKBManifestationID)11716163 035 $a(PQKBTitleCode)TC0001386612 035 $a(PQKBWorkID)11374702 035 $a(PQKB)10249205 035 $a(DE-He213)978-3-662-43733-9 035 $a(MiAaPQ)EBC1966018 035 $a(PPN)183087003 035 $a(EXLCZ)993710000000306291 100 $a20141127d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aMedication-Related Osteonecrosis of the Jaws $eBisphosphonates, Denosumab, and New Agents /$fedited by Sven Otto 205 $a1st ed. 2015. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2015. 215 $a1 online resource (216 p.) 300 $aDescription based upon print version of record. 311 $a3-662-43732-5 320 $aIncludes bibliographical references and index. 327 $aPharmacology of Antiresorptive Drugs -- The Role of Antiresorptive Drugs in the Treatment of Osteoporosis -- The Role of Antiresorptive Drugs in the Treatment of Skeletal Manifestations of Malignant Diseases -- Clinical Features, Localization, Definition and Staging of the Disease -- Radiological Findings / Imaging -- General Characteristics and Risk Factors for BRONJ -- Epidemiology -- Histopathology of BRONJ -- Prevention of Osteonecrosis and Dentoalveolar Surgery Under Treatment With Antiresorptive Drugs -- Bisphosphonates and Dental Implants -- Treatment of BRONJ -- Local and Microvascular Flaps in ONJ-Treatment -- Rehabilitation of Patients After BRONJ -- Adjuvant Treatment Strategies -- Microbiology and Antibiotics -- Animal Models of ONJ -- ONJ Under Denosumab and Other New Drugs -- Possible Use of Antiresorptive Drugs in OMS -- Dental Treatment Under BPs and After BRONJ -- Dental Rehabilitation Under Bisphosphonates and After BRONJ -- History of ONJ. 330 $aOsteonecrosis of the jaws is a well-known side-effect of antiresorptive therapy that predominantly occurs in patients suffering from malignant diseases and receiving intravenous administrations of nitrogen-containing bisphosphonates or subcutaneous administrations of denosumab, a monoclonal antibody. Less frequently it may also be observed in patients with osteoporosis who are being treated with these antiresorptive drugs.  This textbook provides detailed, up-to-date information on all aspects of medication-related osteonecrosis of the jaws, including clinical features, pathogenesis, treatment options, and preventive measures. It also explains safe prevention and treatment strategies for patients receiving antiresorptive drugs who require extractions, implant insertions, and other dento-alveolar surgeries. This book will be of major interest for medical and dental students, dentists, and oral and maxillofacial surgeons as well as osteologists and oncologists. 606 $aMouth$xSurgery 606 $aMaxillofacial surgery 606 $aDentistry 606 $aOral and Maxillofacial Surgery$3https://scigraph.springernature.com/ontologies/product-market-codes/H59060 606 $aDentistry$3https://scigraph.springernature.com/ontologies/product-market-codes/D00009 615 0$aMouth$xSurgery. 615 0$aMaxillofacial surgery. 615 0$aDentistry. 615 14$aOral and Maxillofacial Surgery. 615 24$aDentistry. 676 $a610 676 $a617.522059 676 $a617.6 702 $aOtto$b Sven$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300186603321 996 $aMedication-Related Osteonecrosis of the Jaws$92525341 997 $aUNINA