LEADER 01110cam0-22003971i-450- 001 990006147210403321 005 20051212123917.0 010 $a88-14-04363-9 035 $a000614721 035 $aFED01000614721 035 $a(Aleph)000614721FED01 035 $a000614721 100 $a20000112d1993----km-y0itay50------ba 101 0 $aita 102 $aIT 105 $ay-------001yy 200 1 $aTeorie del valore$ela teoria del costo di produzione e la teoria della domanda e dell'offerta$eda Smith a Ricardo e Marx$fManlio Sechi 210 $aMilano$cGiuffrè$d1993 215 $aXVI, 489 p.$d24 cm 610 0 $aValore$aTeorie economiche 610 0 $aEconomia$aTeorie 676 $a338.51 700 1$aSechi,$bManlio$0128582 801 0$aIT$bUNINA$gRICA$2UNIMARC 901 $aBK 912 $a990006147210403321 952 $aXV F1 75$b23064*$fFGBC 952 $aD/0 SEC$b14215$fSES 952 $aC 164$bs.i.$fDSS 952 $aXI B 439$b22249$fFSPBC 959 $aDSS 959 $aSES 959 $aFSPBC 959 $aFGBC 996 $aTeorie del valore$9645733 997 $aUNINA LEADER 03784nam 22006735 450 001 9910300183103321 005 20200701085207.0 010 $a3-319-12679-2 024 7 $a10.1007/978-3-319-12679-1 035 $a(CKB)3710000000315943 035 $a(EBL)1966000 035 $a(SSID)ssj0001408324 035 $a(PQKBManifestationID)11746697 035 $a(PQKBTitleCode)TC0001408324 035 $a(PQKBWorkID)11346665 035 $a(PQKB)10877915 035 $a(DE-He213)978-3-319-12679-1 035 $a(MiAaPQ)EBC1966000 035 $a(PPN)183153359 035 $a(EXLCZ)993710000000315943 100 $a20141211d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aNeuroanatomy and Pathology of Sporadic Alzheimer's Disease /$fby Heiko Braak, Kelly Del Tredici 205 $a1st ed. 2015. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2015. 215 $a1 online resource (168 p.) 225 1 $aAdvances in Anatomy, Embryology and Cell Biology,$x0301-5556 ;$v215 300 $a"With 48 figures." 311 $a3-319-12678-4 320 $aIncludes bibliographical references. 327 $aPrologue -- General Morphology of Alzheimer-associated intraneuronal pathology -- Consistent and systematic changes in the distribution pattern of intraneuronal inclusions render staging possible -- Basic organization of involved structures -- Presymptomatic stages -- General morphology of Alzheimer-associated extracellular pathology -- Symptomatic stages -- The progression of cortical lesions mimics the pattern of myelination in reverse order -- Tauopathies -- CSF biomarkers and imaging techniques -- The staging hypothesis: assumptions, challenges, potential -- Technical considerations.   . 330 $aAs indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail. 410 0$aAdvances in Anatomy, Embryology and Cell Biology,$x0301-5556 ;$v215 606 $aNeurosciences 606 $aPathology 606 $aGeriatrics 606 $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006 606 $aPathology$3https://scigraph.springernature.com/ontologies/product-market-codes/H4800X 606 $aGeriatrics/Gerontology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33150 615 0$aNeurosciences. 615 0$aPathology. 615 0$aGeriatrics. 615 14$aNeurosciences. 615 24$aPathology. 615 24$aGeriatrics/Gerontology. 676 $a616.83107 700 $aBraak$b Heiko$4aut$4http://id.loc.gov/vocabulary/relators/aut$01058353 702 $aDel Tredici$b Kelly$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910300183103321 996 $aNeuroanatomy and Pathology of Sporadic Alzheimer's Disease$92499521 997 $aUNINA