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010   $a1-4471-6380-X
024 7 $a10.1007/978-1-4471-6380-0
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035   $a(DE-He213)978-1-4471-6380-0
035   $a(PPN)178317667
035   $a(EXLCZ)993710000000105440
100   $a20140423d2014      u|         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 10$aNeurodegenerative Diseases $eClinical Aspects, Molecular Genetics and Biomarkers /$fedited by Daniela Galimberti, Elio Scarpini
205   $a1st ed. 2014.
210  1$aLondon :$cSpringer London :$cImprint: Springer,$d2014.
215   $a1 online resource (266 p.)
300   $aDescription based upon print version of record.
311   $a1-4471-6379-6 
320   $aIncludes bibliographical references at the end of each chapters and index.
327   $aGenetics and Epigenetics: Basic Concepts -- Alzheimer?s Disease: Clinical Aspects and Treatments -- Autosomal Dominant Alzheimer?s Disease: Underlying Causes -- Genetic Risk Factors for Alzheimer?s Disease -- The Role of Cerebrovascular Disease in Cognitive Disease -- Non-genetic Risk Factors for Alzheimer?s disease -- Frontotemporal Lobar Degeneration: Genetics and Clinical Phenotypes -- Alzheimer?s Disease and Frontotemporal Lobar Degeneration: Mouse Models -- Cerebrospinal Fluid Biomarkers in Alzheimer?s Disease and Frontotemporal Dementia -- Biomarkers for Alzheimer?s Disease and Frontotemporal Lobar Degeneration: Imaging -- Amyotrophic Lateral Sclerosis: Genotypes and Phenotypes -- Uncommon Dementias -- Neurodevelopment Alterations, Neurodegeneration and Immunoinflammatory Patterns in the Pathophysiology of Schizophrenia -- Neurodegeneration and Multiple Sclerosis.
330   $aThis book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer?s disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis.   Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
606   $aNeurology 
606   $aNeurosciences
606   $aHuman genetics
606   $aNeurology$3https://scigraph.springernature.com/ontologies/product-market-codes/H36001
606   $aNeurosciences$3https://scigraph.springernature.com/ontologies/product-market-codes/B18006
606   $aHuman Genetics$3https://scigraph.springernature.com/ontologies/product-market-codes/B12008
615  0$aNeurology .
615  0$aNeurosciences.
615  0$aHuman genetics.
615 14$aNeurology.
615 24$aNeurosciences.
615 24$aHuman Genetics.
676   $a599935
676   $a610
676   $a611.01816
676   $a612.8
702   $aGalimberti$b Daniela$4edt$4http://id.loc.gov/vocabulary/relators/edt
702   $aScarpini$b Elio$4edt$4http://id.loc.gov/vocabulary/relators/edt
906   $aBOOK
912   $a9910300096403321
996   $aNeurodegenerative Diseases$91522227
997   $aUNINA