LEADER 04485nam 22006735 450 001 9910767588003321 005 20201106134243.0 010 $a3-540-39982-8 024 7 $a10.1007/b96719 035 $a(CKB)1000000000231098 035 $a(SSID)ssj0000324378 035 $a(PQKBManifestationID)12071112 035 $a(PQKBTitleCode)TC0000324378 035 $a(PQKBWorkID)10304919 035 $a(PQKB)10980415 035 $a(DE-He213)978-3-540-39982-7 035 $a(MiAaPQ)EBC5591945 035 $a(PPN)155197584 035 $a(EXLCZ)991000000000231098 100 $a20121227d2004 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aLectures on Probability Theory and Statistics $eEcole d'Eté de Probabilités de Saint-Flour XXXII - 2002 /$fby Boris Tsirelson, Wendelin Werner ; edited by Jean Picard 205 $a1st ed. 2004. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2004. 215 $a1 online resource (VIII, 200 p.) 225 1 $aÉcole d'Été de Probabilités de Saint-Flour,$x0721-5363 ;$v1840 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-540-21316-3 327 $aPreface -- Part I: Boris Tsirelson: Scaling Limit, Noise, Stability -- Introduction -- A First Look -- Abstract Nonsense of the Scaling Limit -- Scaling Limit and Independence -- Example: The Noise Made by a Poison Snake -- Stability -- Generalizing Wiener Chaos -- Example: The Brownian Web as a Black Noise -- Miscellany -- References -- Index -- Part II: Wendelin Werner: Random Planar Curves and Schramm-Loewner Evolutions -- Introduction -- Loewner Chains -- Chordal SLE -- Chordal SLE and Restriction -- SLE and the Brownian Frontier -- Radial SLE -- Some Critical Exponents for SLE -- Brownian Exponents -- SLE, UST and LERW -- SLE and Critical Percolation -- What is Missing -- References. 330 $aThis is yet another indispensable volume for all probabilists and collectors of the Saint-Flour series, and is also of great interest for mathematical physicists. It contains two of the three lecture courses given at the 32nd Probability Summer School in Saint-Flour (July 7-24, 2002). Boris Tsirelson's lectures introduce the notion of nonclassical noise produced by very nonlinear functions of many independent random variables, for instance singular stochastic flows or oriented percolation. Two examples are examined (noise made by a Poisson snake, the Brownian web). A new framework for the scaling limit is proposed, as well as old and new results about noises, stability, and spectral measures. Wendelin Werner's contribution gives a survey of results on conformal invariance, scaling limits and properties of some two-dimensional random curves. It provides a definition and properties of the Schramm-Loewner evolutions, computations (probabilities, critical exponents), the relation with critical exponents of planar Brownian motions, planar self-avoiding walks, critical percolation, loop-erased random walks and uniform spanning trees. 410 0$aÉcole d'Été de Probabilités de Saint-Flour,$x0721-5363 ;$v1840 606 $aProbabilities 606 $aStatistical physics 606 $aDynamics 606 $aProbability Theory and Stochastic Processes$3https://scigraph.springernature.com/ontologies/product-market-codes/M27004 606 $aComplex Systems$3https://scigraph.springernature.com/ontologies/product-market-codes/P33000 606 $aStatistical Physics and Dynamical Systems$3https://scigraph.springernature.com/ontologies/product-market-codes/P19090 610 1 $aProbability theory 615 0$aProbabilities. 615 0$aStatistical physics. 615 0$aDynamics. 615 14$aProbability Theory and Stochastic Processes. 615 24$aComplex Systems. 615 24$aStatistical Physics and Dynamical Systems. 676 $a519.2 686 $a31.70$2bcl 686 $a31.73$2bcl 700 $aTsirelson$b Boris$4aut$4http://id.loc.gov/vocabulary/relators/aut$0478890 702 $aWerner$b Wendelin$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aPicard$b Jean$4edt$4http://id.loc.gov/vocabulary/relators/edt 712 12$aEcole d'e?te? de probabilite?s de Saint-Flour$d(32nd :$f2002) 906 $aBOOK 912 $a9910767588003321 996 $aLectures on Probability Theory and Statistics$92522502 997 $aUNINA LEADER 02368oam 22005414a 450 001 9910973276103321 005 20211203130232.0 010 $a9781575063935 010 $a157506393X 024 7 $a10.1515/9781575063935 035 $a(CKB)3710000000973089 035 $a(MiAaPQ)EBC4772158 035 $a(DLC) 2016014123 035 $a(OCoLC)945571278 035 $a(MdBmJHUP)musev2_79388 035 $a(DE-B1597)584589 035 $a(OCoLC)1266228534 035 $a(DE-B1597)9781575063935 035 $a(Perlego)2058547 035 $a(EXLCZ)993710000000973089 100 $a20160318d2016 uy 0 101 0 $aeng 135 $aurcnu|||||||| 181 $2rdacontent 182 $2rdamedia 183 $2rdacarrier 200 14$aThe Nesbit Tablets$fDavid I. Owen with the assistance of Alexandra Kleinerman 210 1$d2016.$cEisenbrauns,$aWinona Lake, Indiana : 215 $a1 online resource (199 pages) $cillustrations 225 0 $aNisaba ;$v30 311 08$a9781575062945 311 08$a1575062941 320 $aIncludes bibliographical references and indexes. 330 $aIn 1914, William M. Nesbit published his dissertation at Columbia University on 30 archival texts from the Third Dynasty of Ur. Now, more than a century later, the remaining tablets in his collection have been recovered and, thanks to the generosity of the Nesbit family, were made available for publication by David I. Owen. The majority of texts published here is from Puzri?-Dagan (Drehem) with some from Nippur and Umma. They originate from the earliest clandestine finds at those sites. The 98 texts, including a re-edition of the previously published tablets, are provided with a catalogue, hand-copies, selected photographs, along with transliterations, translations and comments, thus providing an important addition to the extensive corpus of Ur III texts from this important period in Mesopotamian history. 410 0$aNisaba ;$v30. 606 $aSumerian language$vTexts 607 $aBabylonia$xCommerce 608 $aElectronic books. 615 0$aSumerian language 676 $a499/.95 700 $aOwen$b David I.$040533 702 $aKleinerman$b Alexandra 801 0$bMdBmJHUP 801 1$bMdBmJHUP 906 $aBOOK 912 $a9910973276103321 996 $aThe Nesbit Tablets$94366401 997 $aUNINA LEADER 06210nam 22006855 450 001 9910300096003321 005 20251116153509.0 010 $a1-4614-8809-5 024 7 $a10.1007/978-1-4614-8809-5 035 $a(CKB)2550000001151687 035 $a(EBL)1538834 035 $a(SSID)ssj0001049347 035 $a(PQKBManifestationID)11609393 035 $a(PQKBTitleCode)TC0001049347 035 $a(PQKBWorkID)11019457 035 $a(PQKB)10359406 035 $a(MiAaPQ)EBC1538834 035 $a(DE-He213)978-1-4614-8809-5 035 $a(PPN)176099751 035 $a(EXLCZ)992550000001151687 100 $a20131024d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aAdvances in Tumor Immunology and Immunotherapy /$fedited by Joseph D. Rosenblatt, Eckhard R. Podack, Glen N. Barber, Augusto Ochoa 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (369 p.) 225 1 $aCurrent Cancer Research,$x2199-2584 300 $aDescription based upon print version of record. 311 08$a1-4614-8808-7 320 $aIncludes bibliographical references and index. 327 $aContents; Introduction; Part IImmune Activation, Suppression and Manipulation of the Immune Antitumor Response; Myeloid-Derived Suppressor Cells in Cancer; 1 Introduction; 2 Preclinical Data; 2.1 Phenotype; 2.2 Expansion and Activation of MDSCs in Tumor Models; 2.3 Mechanisms of Immunosuppression of MDSCs in Cancer; 2.3.1 Metabolism of l -Arginine; 2.3.2 ROS and Peroxynitrite; 3 Clinical Data; 4 Pharmacologic Modulation of MDSCs; 5 Conclusions; References; The Role of B Cells in Shaping the Antitumor Immune Response; 1 Introduction; 2 B Cells and Antitumor Immunity 327 $a3 Mechanisms of B Cell Modulation of Immune Response3.1 Be1 and Be2 Differentiation and Skewing of T Cell Response; 3.2 B Cells and Antigen Presentation; 3.3 B Cells and Expansion of Tregs; 3.4 B10 Cells and Immune Suppression; 3.5 Other Breg Subsets and Role of TGF-?; 3.6 B Cells and Chronic Inflammation; 4 Effects of B Cell Depletion on Antitumor Immunity; 5 B Cell Infiltration in Human Tumors; 6 Conclusions; References; Heat-Shock Protein-Based Cancer Immunotherapy; 1 Heat-Shock Proteins, Sterile Inflammation, and Immunosurveillance; 2 Autologous Purified HSP Vaccines 327 $a3 Allogeneic Cell-Based HSP Vaccines4 Recombinant and Nucleic Acid-Based HSP Vaccines; 5 Conclusions Based on Clinical Evidence; References; Activation of NK Cell Responses and Immunotherapy of Cancer; 1 Background and History of NK Cells; 2 NK Cell Activation; 3 NK Cells and Cancer; 4 Activated NK Cells as a Cancer Immunotherapy; 5 NK Cells and Other Immunotherapeutic Approaches; 6 Conclusion; References; Induction of Tumor Immunity by Targeted Inhibition of Nonsense-Mediated mRNA Decay; 1 Introduction; 2 Nonsense-Mediated mRNA Decay: A Primer; 2.1 Physiological Roles of NMD 327 $a2.2 Role of NMD in Cancer3 Tumor-Targeted NMD Inhibition to Express New Antigens in Disseminated Tumor Lesions; 3.1 The Concept and Rationale; 3.2 Preclinical Proof-of-Concept Studies in Murine Tumor Models; 4 Conclusions and Future Directions; 4.1 Cytotoxic Therapy or Immunotherapy?; 4.2 What If?; References; Employing T Cell Homeostasis as an Antitumor Strategy; 1 Introduction; 2 Homeostasis of T Lymphocytes; 3 Lymphopenia-Induced T Cell Proliferation; 4 Lymphopenia-Induced Pathologies; 5 Lymphopenia-Induced Antitumor Immune Responses; 6 Clinical Evidence/The Human Model 327 $a7 Adoptive Immunotherapy of Cancer8 Vaccine Augmentation; 9 Lymphopenia-Induced Changes in T reg Percentages; 10 The Dose Makes the Poison; 11 Conclusion; References; Adoptive Cell Therapy of Systemic Metastases Using erbB-2-Specific T Cells Redirected with a Chimeric Antibody-Based Receptor; 1 Introduction; 2 Results and Discussion; 2.1 Phenotypic and Functional Profile of the erbB-2-Specific CAR in Transgenic Mice; 2.2 Nai?ve TgN29 Mice Reject Renca-erbB-2 Tumors; 2.3 Adoptive Transfer of Nai?ve Lymphocytes from TgN29 Mice Extends the Survival of Mice with Systemic Lung Metastases 327 $a2.4 Redirected Allogeneic T Cells (Allo-T-Bodies) as Potential Universal Donors 330 $aThis volume explores recent advances in understanding of fundamental immunology  and insights into  the dynamic interactions between tumors and the immune system, that  provide new opportunities  for therapeutic  intervention in cancer.  Chapter topics include evolving paradigms in the innate and adaptive response,   newly appreciated immunosuppressive mechanisms,  and  novel preclinical  strategies for manipulation of the immune system for therapeutic benefit in cancer. In addition, recent successes in the clinic, and emerging opportunities are covered. Future possibilities, such as the use of antibody engineering, fusion proteins,  and the retargeting of immune cells through T-cell receptor engineering are discussed by  leaders in the field,  focusing  on recent clinical experience, promising technologies, and challenges to clinical success. 410 0$aCurrent Cancer Research,$x2199-2584 606 $aCancer$xResearch 606 $aPharmacology 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 615 0$aCancer$xResearch. 615 0$aPharmacology. 615 14$aCancer Research. 615 24$aPharmacology/Toxicology. 676 $a614.5999 676 $a616.994079 702 $aRosenblatt$b Joseph D.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aPodack$b Eckhard R.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aBarber$b Glen N.$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aOchoa$b Augusto$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300096003321 996 $aAdvances in Tumor Immunology and Immunotherapy$91466227 997 $aUNINA