LEADER 05306nam 22006855 450 001 9910300088703321 005 20230810160817.0 010 $a1-4614-7554-6 024 7 $a10.1007/978-1-4614-7554-5 035 $a(CKB)3710000000083341 035 $a(EBL)1636419 035 $a(OCoLC)870409971 035 $a(SSID)ssj0001162761 035 $a(PQKBManifestationID)11629750 035 $a(PQKBTitleCode)TC0001162761 035 $a(PQKBWorkID)11140885 035 $a(PQKB)11108647 035 $a(MiAaPQ)EBC1636419 035 $a(DE-He213)978-1-4614-7554-5 035 $a(PPN)17609802X 035 $a(EXLCZ)993710000000083341 100 $a20140108d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aLipoproteins in Diabetes Mellitus /$fedited by Alicia J. Jenkins, Peter P. Toth, Timothy J. Lyons 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Humana,$d2014. 215 $a1 online resource (468 p.) 225 1 $aContemporary Diabetes,$x2197-7844 300 $aDescription based upon print version of record. 311 $a1-4614-7553-8 320 $aIncludes bibliographical references and index. 327 $aLaboratory Assessment of Lipoproteins in Diabetes -- Lipoprotein Subclasses and Cardiovascular Disease Risk in Insulin Resistance Diabetes --  Insulin Resistance and Atherosclerosis --  Apoproteins and Cell Surface Receptors Regulating Lipoprotein Metabolism in the Setting of Type 2 Diabetes -- Lipoprotein Metabolism and Alterations induced by insulin resistance and diabetes -- Production and Metabolism of Triglyceride-Rich Lipoproteins in both the Normal and Diabetic States -- Lipoprotein(a): Structure, Metabolism and Pathophysiology -- Lipoprotein Glycation in Diabetes Mellitus.-Lipoprotein (LDL and  HDL) Oxidation in Diabetes Mellitus -- The Role of Modified Forms of LDL and Corresponding Autoantibodies in the Development of Complications in Diabetes -- Lipid ? Extracellular Matrix Interactions as Therapeutic Targets in the Atherosclerosis of Diabetes -- Tools for Assessing Lipoprotein Metabolism in Diabetes Mellitus -- Endothelial Dysfunction and Dyslipidaemia in Type 2 Diabetes: Pathogenesis, Significance and Therapy -- Lipoproteins and Diabetic Nephropathy -- Roles of Extravasated and Modified Plasma Lipoproteins in Diabetic Retinopathy -- Effects of Lifestyle (Diet, Plant Sterols, Excercise) and Glycemic Control on Lipoporteins in Diabetes -- About Randomised Clinical Trials Related to Lipoproteins in Diabetes Mellitus -- Statin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients -- The PPAR System in Diabetes -- Fibrate Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients -- Niacin Therapy: Impact on Dyslipidemia and Cardiovascular Events in Diabetic Patients -- Cholesterol Absorption Inhibitors (Ezetimibe) and Bile Acid Binding Resins (Colesevelam HCl) as Therapy for Dyslipidemia in Patients with Diabetes Mellitus -- Emerging Lipoprotein-Related Therapeutics for Patients with Diabetes. 330 $aDiabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction.  Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of  lifestyle modification and the results of clinical trials using established and investigational drugs are discussed.  An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes. 410 0$aContemporary Diabetes,$x2197-7844 606 $aEndocrinology 606 $aBlood-vessels$xDiseases 606 $aCardiology 606 $aEndocrinology 606 $aAngiology 606 $aCardiology 615 0$aEndocrinology. 615 0$aBlood-vessels$xDiseases. 615 0$aCardiology. 615 14$aEndocrinology. 615 24$aAngiology. 615 24$aCardiology. 676 $a616.4 676 $a616.4/62 676 $a616.462 702 $aJenkins$b Alicia J$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aToth$b Peter P$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aLyons$b Timothy J$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300088703321 996 $aLipoproteins in Diabetes Mellitus$91521855 997 $aUNINA