LEADER 04859nam 22007335 450 001 9910300081903321 005 20200705150327.0 010 $a3-319-05104-0 024 7 $a10.1007/978-3-319-05104-8 035 $a(CKB)3710000000106738 035 $a(EBL)1731025 035 $a(OCoLC)884587822 035 $a(SSID)ssj0001204822 035 $a(PQKBManifestationID)11739544 035 $a(PQKBTitleCode)TC0001204822 035 $a(PQKBWorkID)11180879 035 $a(PQKB)10875690 035 $a(MiAaPQ)EBC1731025 035 $a(DE-He213)978-3-319-05104-8 035 $a(PPN)178317756 035 $a(EXLCZ)993710000000106738 100 $a20140423d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aCancer Immunotherapy Meets Oncology$b[electronic resource] $eIn Honor of Christoph Huber /$fedited by Cedrik Michael Britten, Sebastian Kreiter, Mustafa Diken, Hans-Georg Rammensee 205 $a1st ed. 2014. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2014. 215 $a1 online resource (243 p.) 300 $aDescription based upon print version of record. 311 $a3-319-05103-2 320 $aIncludes bibliographical references at the end of each chapters. 327 $aImmunological and Regulatory Framework for Immuno-Oncology: From Basic Immunology to New Therapies for Patients -- How T cells single out tumor cells: 'and that has made all the difference' -- Tregs and Immune Inhibition -- Regulatory Landscape for Cancer Immunotherapy -- Immunoguiding -- Onco-Immunology Framework and Immunomodulatory Antibodies -- Immunotherapies: Peptide-based Vaccines and HPV Malignancies.- Dendritic cell based cancer vaccines.- RNA Vaccines and Personalized Medicine Approaches.-Antibody Therapy in Oncology.- Engineered Antibodies to Engage Immune Cells to the Tumor -- TCRs and TCR Therapy -- CAR Therapy.- Cancer Entities: Melanoma -- Prostate Cancer/Sipuleucel and RNA Vaccines -- Recent advances in the immunotherapy of renal cell cancer and other solid tumors -- Gastric Cancer -- NSCLC -- Breaking tolerance by allogeneic lymphocyte therapy.- Biomarkers: Exploring Immunogenic Cell Death for Patient Benefit -- Circulating Tumor Cells -- Genomics Meets Oncology -- Featured Chapters: Oncolytic Viruses -- Pharma View on Immunotherapy -- Final Remarks. 330 $aThis book provides a comprehensive update on the state of the art in cancer immunology, which has rapidly evolved from a field of clinical research into an established discipline of oncology. The key recent developments in immuno-oncology are all covered, from the ever-changing immunological and regulatory frameworks to the most promising therapeutic concepts. Themes include combination therapies and personalized medicine, as well as identification of biomarkers to guide the clinical development of new approaches and to pinpoint the optimal treatment for each patient. The book acknowledges the continuing dynamic nature of the field as reflected in the development of next-generation immunotherapies that are already in clinical testing.   Cancer Immunotherapy Meets Oncology is dedicated to the lifetime achievements of Christoph Huber, founder and chair of the Association for Cancer Immunotherapy (CIMT). It is also a tribute to those researchers and clinicians who are striving to develop novel diagnostics and tailored immunotherapies for the benefit of cancer patients. 606 $aOncology   606 $aCancer research 606 $aPharmacology 606 $aImmunology 606 $aOncology$3https://scigraph.springernature.com/ontologies/product-market-codes/H33160 606 $aCancer Research$3https://scigraph.springernature.com/ontologies/product-market-codes/B11001 606 $aPharmacology/Toxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21007 606 $aImmunology$3https://scigraph.springernature.com/ontologies/product-market-codes/B14000 615 0$aOncology  . 615 0$aCancer research. 615 0$aPharmacology. 615 0$aImmunology. 615 14$aOncology. 615 24$aCancer Research. 615 24$aPharmacology/Toxicology. 615 24$aImmunology. 676 $a610 676 $a614.5999 676 $a615 676 $a616079 702 $aBritten$b Cedrik Michael$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKreiter$b Sebastian$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aDiken$b Mustafa$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRammensee$b Hans-Georg$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300081903321 996 $aCancer Immunotherapy Meets Oncology$91522007 997 $aUNINA