LEADER 06905nam 22007455 450 001 9910300071703321 005 20200629234346.0 010 $a1-4939-0656-9 024 7 $a10.1007/978-1-4939-0656-7 035 $a(CKB)2560000000148540 035 $a(EBL)1730902 035 $a(OCoLC)902412177 035 $a(SSID)ssj0001205058 035 $a(PQKBManifestationID)11962958 035 $a(PQKBTitleCode)TC0001205058 035 $a(PQKBWorkID)11180790 035 $a(PQKB)10356696 035 $a(MiAaPQ)EBC1730902 035 $a(DE-He213)978-1-4939-0656-7 035 $a(PPN)178317802 035 $a(EXLCZ)992560000000148540 100 $a20140416d2014 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aSchizophrenia $eRecent Advances in Diagnosis and Treatment /$fedited by Philip G. Janicak, Stephen R. Marder, Rajiv Tandon, Morris Goldman 205 $a1st ed. 2014. 210 1$aNew York, NY :$cSpringer New York :$cImprint: Springer,$d2014. 215 $a1 online resource (333 p.) 300 $aDescription based upon print version of record. 311 $a1-4939-0655-0 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $a""Preface""; ""Contents""; ""Contributors""; ""Part I: Overview""; ""Chapter 1: Introduction""; ""Clinical Features""; "" Epidemiology and Genetic and Environmental Risk Factors""; "" Overview of Neurobiology""; ""Neurotransmission""; "" Genetics""; "" Neuroimaging""; "" Endophenotypes""; "" Management of Schizophrenia""; "" Complications Associated with Schizophrenia and Its Treatment""; ""Long-Term Management""; ""References""; ""Chapter 2: The Evolving Nosology of Schizophrenia: Relevance for Treatment""; ""Introduction"" 327 $a"" The Concept of Schizophrenia from the Nineteenth Century to DSM-IV and ICD-10"""" The Present: DSM-5 and Towards ICD-11""; ""Changes in Characteristic Symptoms of Schizophrenia in DSM-5 and ICD-11""; "" Elimination of Classic Subtypes of Schizophrenia in DSM-5 and ICD-11""; "" Addition of Psychopathological Dimensions of Schizophrenia""; "" Attenuated Psychosis Syndrome""; "" Treatment Implications of Current Conceptualization of Schizophrenia: 2014 and Beyond""; ""References""; ""Part II: Recent Research into thePathophysiology of Schizophrenia""; ""Chapter 3: Overview of Neurobiology"" 327 $a""Introduction""""Identifying Findings Is Not the Same as Identifying an Abnormality""; "" To Determine If a Finding Reflects Pathology, Learn About Its Regulation""; "" Some Abnormalities May Be Epiphenomena But Still Provide Clues About Mechanisms""; "" Heterogeneity Obscures Findings by Mixing Patients with Deficient and Adaptive Function""; "" Compensatory Responses May Identify Potential Treatment Interventions for Other Patients""; "" How Does One Relate Underlying Neurobiology to Treatment of Schizophrenia""; "" Conclusion""; ""References"" 327 $a""Chapter 4: Pathophysiology of Schizophrenia""""Introduction""; "" Brain Structure""; ""Gray Matter""; "" White Matter""; "" Summary""; "" Brain Function""; ""Functional and Molecular Imaging""; "" Summary""; "" Neurophysiology""; ""P300""; "" Prepulse Inhibition of Startle""; "" P50 Auditory-Evoked Potential Suppression""; "" Mismatch Negativity""; "" Cortical Oscillations and Neural Synchrony""; "" Summary""; "" Oxidative, Immunological, and Neuroendocrine Abnormalities""; "" Neurotransmitter Systems""; ""Neurochemical Imaging""; "" Dopamine""; "" Gamma Aminobutyric Acid""; "" Glutamate"" 327 $a"" Summary"""" Neuropathology""; "" Neuroplasticity""; "" Models of Pathogenesis""; ""Summary""; "" Conclusion""; ""Knowledge Gaps and Future Steps""; ""References""; ""Chapter 5: Genetics of Schizophrenia""; ""Introduction""; "" Genetic Epidemiology""; "" Molecular Approaches: Linkage""; "" Molecular Approaches: Candidate Gene Association""; "" Molecular Approaches: Genome-Wide Association Studies""; "" Genetic Relationships to Bipolar Disorder""; "" Clinical Applications and Future Directions""; "" Conclusion""; ""Glossary""; ""References"" 327 $a""Chapter 6: Recent Advances in Neuroimaging Biomarkers of Schizophrenia"" 330 $aSchizophrenia: Recent Advances in Diagnosis and Treatment is a major addition to the literature, offering practical, comprehensive coverage of diagnosis and treatment options, genetic issues, neuroimaging, long-term management of schizophrenia, and future directions and predictions of how clinical care of schizophrenia will change.  The book is divided into five sections. Section 1 summarizes the present state of knowledge about the diagnosis and treatment of schizophrenia. This includes recent changes in the DSM 5 categorization of schizophrenia and its implications for treatment. Section 2 considers recent discoveries into its pathoetiology, including the status of biological markers, genetics and neuroimaging as they relate to diagnosis and potential novel therapeutic approaches. Section 3 explores the optimization of present therapeutic approaches; novel treatments; and management of the substantial risks associated with both the illness and its present therapies. Section 4 discusses progress in the long-term management of schizophrenia, focusing on biological and psychotherapeutic strategies to improve functioning and facilitate recovery.  Section 5 considers future directions and predictions of how diagnosis and treatment of schizophrenia will change.  An invaluable addition to the field, Schizophrenia: Recent Advances in Diagnosis and Treatment is a definitive resource that will be of great interest to all clinicians caring for patients with schizophrenia. 606 $aPsychiatry 606 $aPsychopharmacology 606 $aPsychotherapy    606 $aPsychiatry$3https://scigraph.springernature.com/ontologies/product-market-codes/H53003 606 $aPsychopharmacology$3https://scigraph.springernature.com/ontologies/product-market-codes/H53010 606 $aPsychotherapy$3https://scigraph.springernature.com/ontologies/product-market-codes/H5400X 615 0$aPsychiatry. 615 0$aPsychopharmacology. 615 0$aPsychotherapy   . 615 14$aPsychiatry. 615 24$aPsychopharmacology. 615 24$aPsychotherapy. 676 $a610 676 $a615.78 676 $a616.89 676 $a616.8914 702 $aJanicak$b Philip G$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aMarder$b Stephen R$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aTandon$b Rajiv$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aGoldman$b Morris$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910300071703321 996 $aSchizophrenia$91411695 997 $aUNINA