LEADER 06073nam 22006615 450 001 9910299913203321 005 20200705161717.0 010 $a3-319-59548-2 024 7 $a10.1007/978-3-319-59548-1 035 $a(CKB)3710000001630966 035 $a(DE-He213)978-3-319-59548-1 035 $a(MiAaPQ)EBC4987748 035 $a(PPN)20385098X 035 $a(EXLCZ)993710000001630966 100 $a20170830d2018 u| 0 101 0 $aeng 135 $aurnn#008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aBiomedical Technology $eModeling, Experiments and Simulation /$fedited by Peter Wriggers, Thomas Lenarz 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (IX, 362 p. 166 illus., 135 illus. in color.) 225 1 $aLecture Notes in Applied and Computational Mechanics,$x1613-7736 ;$v84 320 $aIncludes bibliographical references at the end of each chapters. 327 $aMultiscale Aspects in the Multiphasic Modelling of Human Brain Tissue -- Simulation of Steatosis Zonation in Liver Lobule - a Continuummechanical Biscale, Tri-phasic, Multi-component Approach -- Nano-mechanical Tensile Behavior of the SPTA1 Gene in the Presence of Hereditary hemolytic anemia-related Point Mutations -- The Choice of a Performance Indicator of Release in Transdermal Drug Delivery Systems -- Multiscale Multiphysic Approaches in Vascular Hemodynamics -- Heart Valve Flow Computation with the Space-Time Slip Interface Topology Change (ST-SI-TC) Method and Isogeometric Analysis (IGA) -- Estimation of Element-based Zero-stress State in Arterial FSI Computations with Isogeometric Wall Discretization -- Fluid-Structure Interaction Modeling in 3D Cerebral Arteries and Aneurysms -- Large-eddy Simulation of Turbulence in Cardiovascular Flows -- Computational Comparison between Newtonian and non-Newtonian Blood Rheologies in Stenotic Vessels -- Artificial Textile Reinforced Tubular Aortic Heart Valves - Multi-scale Modelling and Experimental Validation -- Preliminary Monolithic Fluid Structure Interaction Model for Ventricle Contraction -- The Biomechanical Rupture Risk Assessment of Abdominal Aortic Aneurysms - Method and Clinical Relevance -- A deeper Insight of a Multi-dimensional Continuous Biofilm Growth Model: Experimental Observation and Parameter Studies -- Multiscale Experimental and Computational Investigation of Nature's Design Principle of Hierarchies in Dental Enamel -- Challenges in Total Hip Arthroplasty -- Personalized Orthopaedic Trauma Surgery by Applied Clinical Mechanics -- Measurement of Intracochlear Pressure Differences in Human Temporal Bones using an off-the-shelf Pressure Sensor -- Development of a Parametric Model of the Electrically Stimulated Auditory Nerve. 330 $aThis book provides an overview of new mathematical models, computational simulations and experimental tests in the field of biomedical technology, and covers a wide range of current research and challenges. The first part focuses on the virtual environment used to study biological systems at different scales and under multiphysics conditions. In turn, the second part is devoted to modeling and computational approaches in the field of cardiovascular medicine, e.g. simulation of turbulence in cardiovascular flow, modeling of artificial textile-reinforced heart valves, and new strategies for reducing the computational cost in the fluid-structure interaction modeling of hemodynamics. The book?s last three parts address experimental observations, numerical tests, computational simulations, and multiscale modeling approaches to dentistry, orthopedics and otology. Written by leading experts, the book reflects the remarkable advances that have been made in the field of medicine, the life sciences, engineering and computational mechanics over the past decade, and summarizes essential tools and methods (such as virtual prototyping of medical devices, advances in medical imaging, high-performance computing and new experimental test devices) to enhance medical decision-making processes and refine implant design. The contents build upon the International Conference on Biomedical Technology 2015 (ICTB 2015), the second ECCOMAS thematic conference on Biomedical Engineering, held in Hannover, Germany in October 2015. 410 0$aLecture Notes in Applied and Computational Mechanics,$x1613-7736 ;$v84 606 $aMechanics 606 $aMechanics, Applied 606 $aBiomedical engineering 606 $aRegenerative medicine 606 $aTissue engineering 606 $aHealth informatics 606 $aSolid Mechanics$3https://scigraph.springernature.com/ontologies/product-market-codes/T15010 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aHealth Informatics$3https://scigraph.springernature.com/ontologies/product-market-codes/H28009 606 $aBiomedical Engineering/Biotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/B24000 615 0$aMechanics. 615 0$aMechanics, Applied. 615 0$aBiomedical engineering. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aHealth informatics. 615 14$aSolid Mechanics. 615 24$aBiomedical Engineering and Bioengineering. 615 24$aRegenerative Medicine/Tissue Engineering. 615 24$aHealth Informatics. 615 24$aBiomedical Engineering/Biotechnology. 676 $a620.1 702 $aWriggers$b Peter$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aLenarz$b Thomas$4edt$4http://id.loc.gov/vocabulary/relators/edt 906 $aBOOK 912 $a9910299913203321 996 $aBiomedical Technology$91412809 997 $aUNINA