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024 7 $a10.1007/978-3-642-28554-7
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035   $a(EBL)1082439
035   $a(OCoLC)854520121
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100   $a20111102d2014      uy         0
101 0 $aeng
135   $aur|n|---|||||
181   $ctxt
182   $cc
183   $acr
200 00$aComputational methods to study the structure and dynamics of biomolecules and biomolecular processes $efrom bioinformatics to molecular quantum mechanics /$fAdam Liwo, editor
205   $a1st ed. 2014.
210   $aBerlin ;$aHeidleberg $cSpringer-Verlag$d2014
215   $a1 online resource (809 p.)
225 0 $aSpringer series in bio-/neuroinformatics ;$v1
300   $aDescription based upon print version of record.
311 08$a3-642-28553-8 
320   $aIncludes bibliographical references and index.
327   $aMolecular simulations: methodology -- Molecular simulations: applications -- Use of structural database or experimental information in modeling protein structure and dynamics -- Applications of molecular quantum mechanics.
330   $aSince the second half of the 20th century machine computations have played a critical role in science and engineering. Computer-based techniques have become especially important in molecular biology, since they often represent the only viable way to gain insights into the behavior of a biological system as a whole. The complexity of biological systems, which usually needs to be analyzed on different time- and size-scales and with different levels of accuracy, requires the application of different approaches, ranging from comparative analysis of sequences and structural databases, to the analysis of networks of interdependence between cell components and processes, through coarse-grained modeling to atomically detailed simulations, and finally to molecular quantum mechanics. This book provides a comprehensive overview of modern computer-based techniques for computing the structure, properties and dynamics of biomolecules and biomolecular processes. The twenty-two chapters, written by scientists from all over the world, address the theory and practice of computer simulation techniques in the study of biological phenomena. The chapters are grouped into four thematic sections dealing with the following topics: the methodology of molecular simulations; applications of molecular simulations; bioinformatics methods and use of experimental information in molecular simulations; and selected applications of molecular quantum mechanics. The book includes an introductory chapter written by Harold A. Scheraga, one of the true pioneers in simulation studies of biomacromolecules.
410  0$aSpringer Series in Bio-/Neuroinformatics,$x2193-9349 ;$v1
606   $aBiomolecules$xStructure$xComputer simulation
606   $aMolecular dynamics$xComputer simulation
615  0$aBiomolecules$xStructure$xComputer simulation.
615  0$aMolecular dynamics$xComputer simulation.
676   $a572
701   $aLiwo$b Adam$01756269
801  0$bMiAaPQ
801  1$bMiAaPQ
801  2$bMiAaPQ
906   $aBOOK
912   $a9910299718503321
996   $aComputational methods to study the structure and dynamics of biomolecules and biomolecular processes$94193469
997   $aUNINA