LEADER 04623nam 22008055 450 001 9910299704603321 005 20200706200734.0 010 $a4-431-55163-8 024 7 $a10.1007/978-4-431-55163-8 035 $a(CKB)3710000000356843 035 $a(EBL)1973988 035 $a(SSID)ssj0001452100 035 $a(PQKBManifestationID)11808769 035 $a(PQKBTitleCode)TC0001452100 035 $a(PQKBWorkID)11478733 035 $a(PQKB)10336163 035 $a(DE-He213)978-4-431-55163-8 035 $a(MiAaPQ)EBC1973988 035 $a(PPN)184497221 035 $a(EXLCZ)993710000000356843 100 $a20150210d2015 u| 0 101 0 $aeng 135 $aur|n|---||||| 181 $ctxt 182 $cc 183 $acr 200 10$aInnovative Approaches to Cell Biomechanics$b[electronic resource] $eFrom Cell Migration to On-Chip Manipulation /$fby Kennedy Omondi Okeyo, Hiromi Miyoshi, Taiji Adachi 205 $a1st ed. 2015. 210 1$aTokyo :$cSpringer Japan :$cImprint: Springer,$d2015. 215 $a1 online resource (201 p.) 225 1 $aFrontiers of Biomechanics,$x2199-8515 ;$v1 300 $aDescription based upon print version of record. 311 $a4-431-55162-X 320 $aIncludes bibliographical references at the end of each chapters and index. 327 $aActin Cytoskeletal Structure in Migrating Cells -- Actin Cytoskeleton Generates Mechanical Forces for Cell Migration -- Multi-scale Mechanochemical Interactions between Cell Membrane and Actin Filaments -- Actin Network Flow and Turnover are coupled in Migrating Cells -- Mechanical Strain is involved in Actin Network Reorganization -- Actin Network Dynamics is Regulated by Actomyosin Interactions -- Biophysical Interactions between Cells and Extracellular Matrix -- Cell Migration in Engineered Micro-/Nano-environments with Controlled Physical Properties -- Engineered Biomaterial for Cell Manipulation. 330 $aThis book covers topics on mechanosensing, mechanotransduction, and actin cytoskeletal dynamics in cell motility. It will contribute to a better understanding of how cells functionally adapt to their mechanical environment as well as highlighting fundamental concepts for designing material niches for cell manipulation. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, the book is the first of its kind, providing comprehensive, integrated coverage of innovative approaches to cell biomechanics. It provides a valuable resource for seniors and graduate students studying cell biomechanics, and is also suitable for researchers interested in the application of methods and strategies in connection with the innovative approaches discussed. Each section of the book has been supplemented with concrete examples and illustrations to facilitate understanding even for readers unfamiliar with cell biomechanics. 410 0$aFrontiers of Biomechanics,$x2199-8515 ;$v1 606 $aBiomedical engineering 606 $aRegenerative medicine 606 $aTissue engineering 606 $aBiophysics 606 $aBiological physics 606 $aHuman physiology 606 $aBiomedical Engineering and Bioengineering$3https://scigraph.springernature.com/ontologies/product-market-codes/T2700X 606 $aRegenerative Medicine/Tissue Engineering$3https://scigraph.springernature.com/ontologies/product-market-codes/L16080 606 $aBiological and Medical Physics, Biophysics$3https://scigraph.springernature.com/ontologies/product-market-codes/P27008 606 $aHuman Physiology$3https://scigraph.springernature.com/ontologies/product-market-codes/B13004 615 0$aBiomedical engineering. 615 0$aRegenerative medicine. 615 0$aTissue engineering. 615 0$aBiophysics. 615 0$aBiological physics. 615 0$aHuman physiology. 615 14$aBiomedical Engineering and Bioengineering. 615 24$aRegenerative Medicine/Tissue Engineering. 615 24$aBiological and Medical Physics, Biophysics. 615 24$aHuman Physiology. 676 $a571.4 676 $a571538 676 $a610.28 676 $a612 676 $a612.028 676 $a620 700 $aOkeyo$b Kennedy Omondi$4aut$4http://id.loc.gov/vocabulary/relators/aut$0739847 702 $aMiyoshi$b Hiromi$4aut$4http://id.loc.gov/vocabulary/relators/aut 702 $aAdachi$b Taiji$4aut$4http://id.loc.gov/vocabulary/relators/aut 906 $aBOOK 912 $a9910299704603321 996 $aInnovative Approaches to Cell Biomechanics$92531503 997 $aUNINA