LEADER 05183nam 22005175 450 001 9910299412503321 005 20200707024127.0 010 $a3-319-64377-0 024 7 $a10.1007/978-3-319-64377-9 035 $a(CKB)4100000001040688 035 $a(DE-He213)978-3-319-64377-9 035 $a(MiAaPQ)EBC5143853 035 $a(PPN)221252657 035 $a(EXLCZ)994100000001040688 100 $a20171110d2018 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aAnticoagulant Rodenticides and Wildlife /$fedited by Nico W. van den Brink, John E. Elliott, Richard F. Shore, Barnett A. Rattner 205 $a1st ed. 2018. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2018. 215 $a1 online resource (XVI, 398 p. 48 illus., 28 illus. in color.) 225 1 $aEmerging Topics in Ecotoxicology, Principles, Approaches and Perspectives,$x1868-1344 ;$v5 311 $a3-319-64375-4 320 $aIncludes bibliographical references and index. 327 $aForeword -- 1. Anticoagulant Rodenticides and Wildlife: Introduction -- 2. Use of anticoagulant rodenticides in different applications around the world -- 3. Anticoagulant rodenticide toxicity to non-target wildlife under controlled exposure conditions -- 4. Pharmacokinetics of anticoagulant rodenticides in target and non-target organisms -- 5. Ante-mortem and post-mortem signs of anticoagulant rodenticide toxicosis in birds of prey -- 6. Primary exposure and effects in non-target animals -- 7. Secondary exposure to anticoagulant rodenticides and effects on predators -- 8. Spatial dimensions of the risks of rodenticide use to non-target small mammals and applications in spatially explicit risk modeling -- 9. Ecological factors driving uptake of anticoagulant rodenticides in predators -- 10. Development of resistance to anticoagulant rodenticides in rodents -- 11. An international perspective on the regulation of rodenticides -- 12. Anticoagulants and risk mitigation -- 13. Perspectives on existing and potential new alternatives to anticoagulant rodenticides and the implications for integrated pest management -- 14. Anticoagulant rodenticides and wildlife: concluding remarks. 330 $aCommensal rodents consume and spoil crops and food supplies, cause  property damage and can be vectors for disease. Rats have also invaded islands and can pose a serious threat to native wildlife, particularly seabirds. Estimates of rodent damage range into the billions of dollars in developed countries. In southern Asia, rodents are estimated to consume or destroy annually sufficient rice to feed 50 million people. The predominant control method for pest rodents in most countries is  anticoagulant rodenticides, which are antagonists of vitamin K metabolism that prevent blood-clotting and cause fatal haemorrhage. This mode of toxicity is common to all vertebrates because of their shared blood clotting mechanism, so anticoagulants pose a potential risk to a wide range of non-target species. This is well recognised and anticoagulants fail regulatory environmental risk assessments in many jurisdictions. Nonetheless, the compounds continue to be heavily used because of the societal need for rodent control and the limited availability of safer alternatives.  As a result, exposure of non-target species is commonplace throughout the world and reflects the extensive use, persistence and bioaccumulation potential of many of these compounds. The consequences of such exposure, in terms of effects on wildlife populations, remain uncertain and the subject of much research, debate and controversy.  Accordingly, there is a  significant and ongoing need for integrated assessment of the threats to wildlife from anticoagulant rodenticides, combined with development of governance, mitigation measures and development of alternatives. This book provides a state-of-the-art overview of the scientific advancements in the assessment of exposure, effects and risks that currently used rodenticides may pose to non-target organisms in the environment. This is discussed in relation to their efficacy, and the societal needs for rodent control, and risk mitigation and development of alternatives. 410 0$aEmerging Topics in Ecotoxicology, Principles, Approaches and Perspectives,$x1868-1344 ;$v5 606 $aEcotoxicology 606 $aEcotoxicology$3https://scigraph.springernature.com/ontologies/product-market-codes/U25001 615 0$aEcotoxicology. 615 14$aEcotoxicology. 676 $a614.438 702 $avan den Brink$b Nico W$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aElliott$b John E$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aShore$b Richard F$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aRattner$b Barnett A$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910299412503321 996 $aAnticoagulant Rodenticides and Wildlife$92533274 997 $aUNINA