LEADER 05010nam 22007695 450 001 9910299204103321 005 20200704014011.0 010 $a1-4471-6762-7 024 7 $a10.1007/978-1-4471-6762-4 035 $a(CKB)3710000000521513 035 $a(SSID)ssj0001584263 035 $a(PQKBManifestationID)16263237 035 $a(PQKBTitleCode)TC0001584263 035 $a(PQKBWorkID)14864194 035 $a(PQKB)10064939 035 $a(DE-He213)978-1-4471-6762-4 035 $a(MiAaPQ)EBC6315632 035 $a(MiAaPQ)EBC5587270 035 $a(Au-PeEL)EBL5587270 035 $a(OCoLC)920566402 035 $a(PPN)190523735 035 $a(EXLCZ)993710000000521513 100 $a20150901d2015 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt 182 $cc 183 $acr 200 10$aGuide to Simulation and Modeling for Biosciences /$fby David J. Barnes, Dominique Chu 205 $a2nd ed. 2015. 210 1$aLondon :$cSpringer London :$cImprint: Springer,$d2015. 215 $a1 online resource (XII, 339 p. 80 illus.) 225 1 $aSimulation Foundations, Methods and Applications,$x2195-2817 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a1-4471-6761-9 320 $aIncludes bibliographical references and index. 327 $aFoundations of Modeling -- Agent-based Modeling -- ABMs using Repast Simphony -- Differential Equations -- Mathematical Tools -- Other Stochastic Methods and Prism -- Simulating Biochemical Systems -- Biochemical Models Beyond the Perfect Mixing Assumption -- Reference Material. 330 $aThis accessible text/reference presents a detailed introduction to the use of a wide range of software tools and modeling environments for use in the biosciences, as well as some of the fundamental mathematical background. The practical constraints and difficulties presented by each modeling technique are described in detail, enabling the researcher to determine quickly which software package would be most useful for their particular problem. This Guide to Simulation and Modeling for Biosciences is a fully updated and enhanced revision of the authors? earlier Introduction to Modeling for Biosciences. Written with the particular needs of the novice modeler in mind, this unique and helpful work guides the reader through realistic and concrete modeling projects, highlighting and commenting on the process of abstracting the real system into a model. Topics and features: Introduces a basic array of techniques to formulate models of biological systems, and to solve them Discusses agent-based models, stochastic modeling techniques, differential equations, spatial simulations, and Gillespie?s stochastic simulation algorithm Provides exercises to help the reader sharpen their understanding of the topics Describes such useful tools as the Maxima algebra system, the PRISM model checker, and the modeling environments Repast Simphony and Smoldyn Contains appendices on rules of differentiation and integration, Maxima and PRISM notation, and some additional mathematical concepts Offers supplementary material at an associated website, including source code for many of the example models discussed in the book Students and active researchers in the biosciences will benefit from the discussions of the high-quality, tried-and-tested modeling tools described in the book, as well as the thorough descriptions and examples. 410 0$aSimulation Foundations, Methods and Applications,$x2195-2817 606 $aComputer simulation 606 $aMathematical models 606 $aBioinformatics 606 $aBioinformatics  606 $aComputational biology  606 $aSimulation and Modeling$3https://scigraph.springernature.com/ontologies/product-market-codes/I19000 606 $aMathematical Modeling and Industrial Mathematics$3https://scigraph.springernature.com/ontologies/product-market-codes/M14068 606 $aComputational Biology/Bioinformatics$3https://scigraph.springernature.com/ontologies/product-market-codes/I23050 606 $aComputer Appl. in Life Sciences$3https://scigraph.springernature.com/ontologies/product-market-codes/L17004 615 0$aComputer simulation. 615 0$aMathematical models. 615 0$aBioinformatics. 615 0$aBioinformatics . 615 0$aComputational biology . 615 14$aSimulation and Modeling. 615 24$aMathematical Modeling and Industrial Mathematics. 615 24$aComputational Biology/Bioinformatics. 615 24$aComputer Appl. in Life Sciences. 676 $a570.113 700 $aBarnes$b David J$4aut$4http://id.loc.gov/vocabulary/relators/aut$0479332 702 $aChu$b Dominique$4aut$4http://id.loc.gov/vocabulary/relators/aut 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910299204103321 996 $aGuide to Simulation and Modeling for Biosciences$92545679 997 $aUNINA