LEADER 00702cam0 22002411 450 001 SOBE00018235 005 20110929124745.0 100 $a20110929d1908 |||||ita|0103 ba 101 $aita 102 $aIT 200 1 $aPoesie$fEnrico Panzacchi 210 $aBologna$cZanichelli$d1908 215 $aXI, 715 p.$19 cm 700 1$aPanzacchi$b, Enrico$3SOBA00000228$4070$0179503 801 0$aIT$bUNISOB$c20110929$gRICA 850 $aUNISOB 852 $aUNISOB$j850$m78899 912 $aSOBE00018235 940 $aM 102 Monografia moderna SBN 941 $aM 957 $a850$b003571$gSI$d78899$1bethb$2UNISOB$3UNISOB$420110929124749.0$520110929124908.0$6bethb 996 $aPoesie$988552 997 $aUNISOB LEADER 04473nam 22006615 450 001 9910298653303321 005 20200706173658.0 010 $a3-642-54050-3 024 7 $a10.1007/978-3-642-54050-9 035 $a(CKB)3710000000085824 035 $a(DE-He213)978-3-642-54050-9 035 $a(SSID)ssj0001186462 035 $a(PQKBManifestationID)11656835 035 $a(PQKBTitleCode)TC0001186462 035 $a(PQKBWorkID)11219186 035 $a(PQKB)10680956 035 $a(MiAaPQ)EBC3092991 035 $a(PPN)176118500 035 $a(EXLCZ)993710000000085824 100 $a20140115d2014 u| 0 101 0 $aeng 135 $aurnn|008mamaa 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aMammalian Cell Cultures for Biologics Manufacturing /$fedited by Weichang Zhou, Anne Kantardjieff 205 $a1st ed. 2014. 210 1$aBerlin, Heidelberg :$cSpringer Berlin Heidelberg :$cImprint: Springer,$d2014. 215 $a1 online resource (VIII, 259 p. 71 illus., 54 illus. in color.) 225 1 $aAdvances in Biochemical Engineering/Biotechnology,$x0724-6145 ;$v139 300 $aBibliographic Level Mode of Issuance: Monograph 311 $a3-642-54049-X 320 $aIncludes bibliographical references and index. 327 $aMammalian Cell Cultures for Biologics Manufacturing -- Mammalian Cell Line Developments in Speed and Efficiency -- Cell Culture Process Operations for Recombinant Protein Production -- Equipment for Large-Scale Mammalian Cell Culture -- Development and Characterization of a Cell Culture Manufacturing Process Using Quality by Design (QbD) Principles -- Product Quality Considerations for Mammalian Cell Culture Process Development and Manufacturing -- Safety Assurance for Biologics Manufactured in Mammalian Cell Cultures: A Multitiered Strategy -- Mammalian Cell Culture Capacity for Biopharmaceutical Manufacturing -- Transcriptomics as a Tool for Assessing the Scalability of Mammalian Cell Perfusion Systems -- Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology. 330 $aAnne Kantardjieff and Weichang Zhou Mammalian Cell Cultures for Biologics Manufacturing Scott Estes and Mark Melville Mammalian Cell Line Developments in Speed and Efficiency Susan Abu-Absi, Sen Xu, Hugh Graham, Nimish Dalal, Marcus Boyer and Kedar Dave Cell Culture Process Operations for Recombinant Protein Production Sadettin S. Ozturk Equipment for Large-Scale Mammalian Cell Culture Daniel M. Marasco, Jinxin Gao, Kristi Griffiths, Christopher Froggatt, Tongtong Wang and Gan Wei Development and Characterization of a Cell Culture Manufacturing Process Using Quality by Design (QbD) Principles Michael J. Gramer Product Quality Considerations for Mammalian Cell Culture Process Development and Manufacturing Dayue Chen Safety Assurance for Biologics Manufactured in Mammalian Cell Cultures: A Multitiered Strategy Dawn M. Ecker and Thomas C. Ransohoff Mammalian Cell Culture Capacity for Biopharmaceutical Manufacturing Karthik P. Jayapal and Chetan T. Goudar Transcriptomics as a Tool for Assessing the Scalability of Mammalian Cell Perfusion Systems Enda Moran and Patrick Gammell Lifecycle Management for Recombinant Protein Production Using Mammalian Cell Culture Technology. 410 0$aAdvances in Biochemical Engineering/Biotechnology,$x0724-6145 ;$v139 606 $aBiotechnology 606 $aCell culture 606 $aPharmaceutical technology 606 $aBiotechnology$3https://scigraph.springernature.com/ontologies/product-market-codes/C12002 606 $aCell Culture$3https://scigraph.springernature.com/ontologies/product-market-codes/L16020 606 $aPharmaceutical Sciences/Technology$3https://scigraph.springernature.com/ontologies/product-market-codes/B21010 615 0$aBiotechnology. 615 0$aCell culture. 615 0$aPharmaceutical technology. 615 14$aBiotechnology. 615 24$aCell Culture. 615 24$aPharmaceutical Sciences/Technology. 676 $a615.3/6 702 $aZhou$b Weichang$4edt$4http://id.loc.gov/vocabulary/relators/edt 702 $aKantardjieff$b Anne$4edt$4http://id.loc.gov/vocabulary/relators/edt 801 0$bMiAaPQ 801 1$bMiAaPQ 801 2$bMiAaPQ 906 $aBOOK 912 $a9910298653303321 996 $aMammalian Cell Cultures for Biologics Manufacturing$92531897 997 $aUNINA LEADER 03280nam 22005415 450 001 9910349558103321 005 20250609112050.0 010 $a3-030-22878-9 024 7 $a10.1007/978-3-030-22878-1 035 $a(CKB)4100000008785957 035 $a(MiAaPQ)EBC5842312 035 $a(DE-He213)978-3-030-22878-1 035 $a(PPN)238492133 035 $a(MiAaPQ)EBC5917906 035 $a(EXLCZ)994100000008785957 100 $a20190729d2019 u| 0 101 0 $aeng 135 $aurcnu|||||||| 181 $ctxt$2rdacontent 182 $cc$2rdamedia 183 $acr$2rdacarrier 200 10$aFluorescence Lifetime Imaging Ophthalmoscopy /$fedited by Martin Zinkernagel, Chantal Dysli 205 $a1st ed. 2019. 210 1$aCham :$cSpringer International Publishing :$cImprint: Springer,$d2019. 215 $a1 online resource (123 pages) 311 08$a3-030-22877-0 327 $aFluorescence lifetime imaging microscopy (FLIM) -- FLIO technique and principles -- Imaging and analysis protocols -- Origin of Retinal fluorophores -- FLIO in the healthy eye -- FLIO in retinal diseases (Age-related macular degeneration (Drusen, early stage, geographic atrophy), Diabetic retinopathy, Retinal artery occlusion, Central serous chorioretinopathy, Macular teleangiectasia, Hereditary retinal diseases (Stargardt, Choroideremia, Retinitis pigmentosa). 330 $aThis book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies. This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. 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